Abstract:
The aim of this study was to examine the effects of high-intensity interval aerobic exercise (HIIE) on peak forearm blood flow (peak FBF) during postprandial hyperglycemia in healthy young men with a parental history of normotension (offspring of normotensive parents; ONT) (n=13) and healthy young men with a parental history of hypertension (offspring of hypertensive parents; OHT) (n=13). This was a randomized crossover study of 2 conditions. The first condition was an oral glucose load with exercise (OGL+EXS), with a 1-week washout, and then an oral glucose load without exercise (OGL). The second condition had the reversed order. All participants underwent the peak FBF measurement during reactive hyperemia using venous occlusion plethysmography before and after OGL and OGL+EXS every 30 minutes for 4 hours. Results: After OGL, the peak FBF in OHT significantly decreased from 23.82±1.39 to 20.61±1.75 ml/100ml/min, (p<0.01) and ONT from 26.84±2.47ml/100ml. to 24.29±2.58 ml/100ml /min, (p<0.01). After OGL with exercise the peak FBF significantly increased from 23.72±1.68 to 27.25±1.91 ml/100ml/min, (p<0.01) in OHT and 26.77±2.86 to 34.07±2.14 ml/100ml/min, (p<0.01) in ONT. Moreover, the peak FBF in ONT was significantly increased more than that in the OHT group (p<0.05). Therefore, HIIE can increase peak FBF in both individuals with and without the family history of hypertension.