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Suthida Boonsith. Preparation of pectin-based hydrogels from pomelo waste for the delivery of chlorhexidine. (). King Mongkut's University of Technology North Bangkok. Central Library. : , 2021.
Preparation of pectin-based hydrogels from pomelo waste for the delivery of chlorhexidine
Name: Nattarika Peaunbida
Organization :
Faculty of Engineering, Mahidol University
Email :
nattarika.pea@student.mahidol.edu
Organization :
Faculty of Engineering, Mahidol University
Name: Worawan Tiatragoon
Organization :
Thailand Institute of Scientific and Technological Research. Expert Center of Innovative Herbal Products
Name: Suthida Boonsith
Organization :
Faculty of Engineering, Mahidol University
Email :
suthida.bos@mahidol.edu
LCSH:
Polygalacturonase
LCSH:
Hydrogels
LCSH:
Biopolymers
LCSH:
Agricultural wastes
LCSH:
Drug delivery systems
LCSH:
Chlorhexidine
Abstract:
Pectin is a polysaccharide that can be obtained through an acid extraction of plant
cell walls and has been used in the formation of hydrogels for various biomedical
applications. In this study, chemical modification of pectin extracted from pomelo (Citrus
maxima) peels was performed through amidation and used for preparation of hydrogels.
Amidated pectin was synthesized and the effect of reaction conditions such as temperature,
time, reactant and reactants concentration were studied. Hydrogels were prepared by mixing
pectin with calcium chloride in acid medium. Chlorhexidine (CHX) was incorporated as a
model drug in formulated hydrogels. Fourier-transform infrared spectroscopy (FTIR) and
organic elemental analysis were performed for structural analysis. In vitro swelling and
release kinetics were carried out at pH 5. 5. In this study, amidated pectin prepared in
ethylenediamine at 5°C for 24 hours provided degree of amidation (DA) of 77.14% which is
greater than ethanolamine (DA 64.83%) under the same condition and slightly changed
when the reaction time was decreased to 12 hours (DA 75.34%). The amidation of pectin
enhanced the stability of pectin hydrogel and demonstrated improved drug loading and
releasing profile. Hydrogel consisted of amidated pectin and pectin (1:1) contained CHX
9.63 mg/1g of hydrogel and can release up to 89.78% while pectin hydrogel contained CHX
4.27 mg/1g of hydrogel and release only 44.79%. It can be concluded that amidated pectin
prepared in ethylenediamine improved CHX loading- releasing in hydrogels and the
utilization of waste originated from pomelo potentially be useful in biomedical industry.
King Mongkut's University of Technology North Bangkok. Central Library
Address:
BANGKOK
Email:
library@kmutnb.ac.th
Created:
2021
Modified:
2026-01-26
Issued:
2026-01-26
บทความ/Article
application/pdf
BibliograpyCitation :
In Thai Institute of Chemical Engineering and Applied Chemistry. The 30th Thai Institute of Chemical Engineering and Applied Chemistry Conference (TIChE 2021) (BIM24). Nakhon Ratchasima : Suranaree University of Technology
eng
©copyrights King Mongkut's University of Technology North Bangkok
RightsAccess:
ใช้เวลา
0.031963 วินาที
Nattarika Peaunbida
| Title | Contributor | Type |
|---|---|---|
| Preparation of pectin-based hydrogels from pomelo waste for the delivery of chlorhexidine
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Nattarika Peaunbida ;Warangkana Pornputtapitak;Worawan Tiatragoon;Suthida Boonsith | บทความ/Article |
Warangkana Pornputtapitak
| Title | Contributor | Type |
|---|---|---|
| Phase behavior of solid-liquid lipid mixtures by coarse-grained molecular dynamics simulations
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Yenruedee Thiangjit;Yuthana Tantirungrotechai;Warangkana Pornputtapitak | บทความ/Article | |
| Optimization of nanostructured lipid carrier using box-behnken design and its potential use as lignin carrier system
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Krittin Intaraopart;Suthida Boonsith;Warangkana Pornputtapitak | บทความ/Article | |
| Development and characterization of amidated pectin-PVA hydrogels for enhanced drug delivery and antimicrobial properties
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Supatcha Suankhem;Woranart Jonglertjunya;Warangkana pornputtapitak;Suthida Boonsith | บทความ/Article | |
| Inhibitory effects of Schinus terebinthifolia leave extract on polyphenol oxidase activity and enzymatic browning
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Supatcha Suankhem;Suthida Boonsith;Warangkana Pornputtapitak | บทความ/Article | |
| Preparation of pectin-based hydrogels from pomelo waste for the delivery of chlorhexidine
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Nattarika Peaunbida ;Warangkana Pornputtapitak;Worawan Tiatragoon;Suthida Boonsith | บทความ/Article |
Worawan Tiatragoon
| Title | Contributor | Type |
|---|---|---|
| Preparation of pectin-based hydrogels from pomelo waste for the delivery of chlorhexidine
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Nattarika Peaunbida ;Warangkana Pornputtapitak;Worawan Tiatragoon;Suthida Boonsith | บทความ/Article |
Suthida Boonsith
| Title | Contributor | Type |
|---|---|---|
| Development and optimization of spray-dried kaffir lime peel essential oil microparticles using emulsion stabilized by modified cassava starch
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Nipaporn Rungjitvaranont;Rattiya Tangratniyom;Sirapat Jitanawasan;Suthida Boonsith | บทความ/Article | |
| Optimization of nanostructured lipid carrier using box-behnken design and its potential use as lignin carrier system
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Krittin Intaraopart;Suthida Boonsith;Warangkana Pornputtapitak | บทความ/Article | |
| Development and characterization of amidated pectin-PVA hydrogels for enhanced drug delivery and antimicrobial properties
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| Inhibitory effects of Schinus terebinthifolia leave extract on polyphenol oxidase activity and enzymatic browning
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Supatcha Suankhem;Suthida Boonsith;Warangkana Pornputtapitak | บทความ/Article | |
| Preparation of pectin-based hydrogels from pomelo waste for the delivery of chlorhexidine
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Nattarika Peaunbida ;Warangkana Pornputtapitak;Worawan Tiatragoon;Suthida Boonsith | บทความ/Article | |
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