แจ้งเอกสารไม่ครบถ้วน, ไม่ตรงกับชื่อเรื่อง หรือมีข้อผิดพลาดเกี่ยวกับเอกสาร ติดต่อที่นี่ ==>
หากไม่มีอีเมลผู้รับให้กรอก thailis-noc@uni.net.th
หากไม่มีอีเมลผู้รับให้กรอก thailis-noc@uni.net.th
Patthanaphon Lusakunwiwat. Investigation of transcriptional responses of cordyceps militaris to different temperatures. Master's Degree(Biology). Kasetsart University. Office of the University Library. : Kasetsart University, 2023.
Investigation of transcriptional responses of cordyceps militaris to different temperatures
Classification :.LCCS: QK623.C55
LCSH:
Cordyceps.
Abstract:
Cordyceps militaris is a valuable medicinal fungus that contains key biometabolites for pharmaceutical applications. Temperature is one of the significant environmental factors that affect fungal growth and metabolite production. However, there is poorly characterized how temperature influences the growth and metabolites of C. militaris, in particular on its metabolic responses at the transcriptional level. This study therefore aimed to investigate the metabolic responses to cordycepin production underlying temperature changes in C. militaris through transcriptome analysis. Here, transcriptome analysis of 9,599 expressed genes in C. militaris strain TBRC6039 grown at different temperatures, including, 15°C and 25°C, was performed. Of these, 576 genes were significantly differentially expressed, uncovering temperatures-mediated changes in the transcriptional regulation of nutrient and energy sources of C. militaris strain TBRC6039 were involved in amino acids metabolism (e.g., glycine, serine and threonine metabolism) and lipid metabolism (e.g., biosynthesis of unsaturated fatty acids and steroid biosynthesis). Our finding suggests that the transcriptional regulation of these pathways is a responsive mechanism in acclimatization to the specific temperature condition during mycelial growth and metabolite production.
Kasetsart University. Office of the University Library
Address:
Bangkok
Email:
tdckulib@ku.ac.th
Name: Wanwipa Vongsangnak
Role:
Thesis Advisor
Name: Kobkul Laoteng
Role:
Thesis Co-Advisor
Created:
2023
Modified:
2025-06-25
Issued:
2025-06-25
วิทยานิพนธ์/Thesis
วิทยานิพนธ์/Thesis
application/pdf
URL: http://www.lib.ku.ac.th/KUthesis/2566/patthanaphon-lus-all.pdf
CallNumber:
QK623.C55.P37
eng
DegreeName: Master of Science
Level: Master's Degree
Descipline: Biology
Grantor: Kasetsart University
©copyrights Kasetsart University
RightsAccess:
ใช้เวลา
0.03539 วินาที
Patthanaphon Lusakunwiwat
| Title | Contributor | Type |
|---|---|---|
| Investigation of transcriptional responses of cordyceps militaris to different temperatures
มหาวิทยาลัยเกษตรศาสตร์ Patthanaphon Lusakunwiwat | Wanwipa Vongsangnak Kobkul Laoteng | วิทยานิพนธ์/Thesis |
Wanwipa Vongsangnak
Kobkul Laoteng
| Title | Creator | Type and Date Create |
|---|---|---|
| Construction of Regulatory Network in Fatty Acid Desaturation of Mucor rouxii via Computational Approach
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าธนบุรี Supapon Cheevadhanarak;Kobkul Laoteng;สุภาภรณ์ ชีวะธนรักษ์;กอบกุล เหล่าเท้ง | Pinnarat Rattanavisud พิณรัตน์ รัตนวิสุทธิ์ | วิทยานิพนธ์/Thesis |
| Investigating light-induced metabolic responses of Cordyceps militaris using transcriptome integrated genome-scale modeling
มหาวิทยาลัยเกษตรศาสตร์ Wanwipa Vongsangnak;Kobkul Laoteng;Teeraphan Laomettachit | Panyawarin Soommat | วิทยานิพนธ์/Thesis |
| Investigation of transcriptional responses of cordyceps militaris to different temperatures
มหาวิทยาลัยเกษตรศาสตร์ Wanwipa Vongsangnak;Kobkul Laoteng | Patthanaphon Lusakunwiwat | วิทยานิพนธ์/Thesis |