Evaluation of microwave assisted extraction of Naringi crenulata leaves for utilization in skincare essence

Evaluation of microwave–assisted extraction of Naringi crenulata leaves for utilization in skincare essence

Name: Khine Mon Yee Hlaing

Address: 333 Moo1, Thasud, Muang, Chiang Rai 57100

Organization : Mae Fah Luang University

Email : library@mfu.ac.th

keyword: Microwave-assisted Extraction

MeSH: Naringi crenulata -- 314997

Classification :.DDC: e-thesis

; Astringent

MeSH: Medicinal plants

MeSH: Antioxidants -- 314711

MeSH: Astringents -- 314998

LCSH: Naringi crenulata -- 314997

LCSH: Medicinal plants

LCSH: Antioxidants -- 314711

LCSH: Astringents -- 314998

Abstract: Naringi crenulata, or Thanaka, is a medicinal plant possessing antioxidant, astringent, and anti-inflammation properties, making it a promising ingredient for cosmetic formulations. This study investigated the extraction of bioactive compounds from N. crenulata leaves, using microwave-assisted extraction with ethanol at varying concentrations (50%, 70%, and 95%). Bioactive compounds such as total phenolic content (TPC), total flavonoid content (TFC), total tannin content (TTC), and astringent activity, antioxidant activity by DPPH radical scavenging, and the ferric reducing antioxidant power (FRAP) assays of the extracts were assessed using colorimetric assays. Among the tested solvents, 50% ethanol achieved the highest extraction yield (16.81%) and maximized bioactive compound recovery (TPC 11.76 ± 0.38 GAE mg/g dry plant, TFC 19.35 ± 0.32 QE mg/g dry plant, 11.51 ± 0.07 TAE mg/g dry plant), along with maximized antioxidant properties (3.35 ± 0.04 AAE mg/g dry plant by DPPH and 3.57 ± 0.05 AAE mg/g dry plant by FRAP method) with IC₅₀ value of 624.6 ± 28.95 µg/mL for DPPH radical scavenging activity. In contrast, 95% ethanol demonstrated the highest astringency 64.94 ± 0.13%. These findings highlight the critical importance of solvent polarity in enhancing the extraction of phenolics, flavonoids, and tannins. The 50% ethanol extract was selected to further formulate into cosmetic formulation because it has the highest antioxidant potential and its integration into essence cosmetic formulations were assessed through heating-cooling cycles and one month of storage at different temperatures (room temperature, 4°C, and 45°C). This study emphasized the overlooked potential of N. crenulata leaves within the field of cosmetic science. Future research may concentrate on techniques to improve stability, evaluate clinical effectiveness, and expand its cosmetic uses.

Mae Fah Luang University. Learning Resources and Educational Media Centre

Address: CHIANG RAI

Email: library@mfu.ac.th

Name: Naphatsorn Ditthawutthikul

Role: Advisor

Created: 2024

Modified: 2025-06-18

Issued: 2025-06-18

วิทยานิพนธ์/Thesis

application/pdf

CallNumber: e-thesis

eng

DegreeName: Master of Science

Level: Master's Degree

Descipline: Creative Innovation in Cosmetic Science

Grantor: Mae Fah Luang University

©copyrights Mae Fah Luang University

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