Phyo Zaw Aung. The efficacy and safety of pure saw palmetto (Serenoa repens) extract lotion in androgenetic alopecia. Master's Degree(Dermatology). Mae Fah Luang University. Learning Resources and Educational Media Centre. : Mae Fah Luang University, 2024.
The efficacy and safety of pure saw palmetto (Serenoa repens) extract lotion in androgenetic alopecia
Efficacy and safety of pure saw palmetto (Serenoa repens) extract lotion in androgenetic alopecia
Abstract:
Background: Herbal remedies have gained the interest of researchers as a potential treatment option for male androgenetic alopecia. These natural alternatives are appealing due to their widespread availability, affordability, and the possibility of fewer side effects compared to some conventional therapies.
Objectives: The aim of this study is to evaluate the efficacy and safety of pure Saw palmetto (Serenoa repens) extract lotion, non-selective inhibitors of 5α reductase types 1 and 2 in the management of androgenetic alopecia (AGA).
Methods: The study involved 18 males with AGA (Norwood-Hamilton Stage IIIIv). For 12 weeks, the participants were instructed to apply hair lotion twice a day. The target area hair count, the global photographic assessment, and the participants satisfaction score were used to evaluate the efficacy.
Results: There was statistically significant improvement in mean hair count (increased total hair count and terminal hair count, and reduced vellus hair count) (p<0.001), global photographic assessment, and participants satisfaction score. There were no significant adverse events during and after the study.
Conclusion: In men with androgenetic alopecia, the use of pure Saw palmetto extract lotion can effectively promote hair growth without significant adverse effects.
Mae Fah Luang University. Learning Resources and Educational Media Centre