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Walaiporn Prissanaroon-Ouajai. Investigation of gelatin hydrogel gelation for drug release system. (). King Mongkut's University of Technology North Bangkok. Central Library. : , 2020.
Investigation of gelatin hydrogel gelation for drug release system
Name: Wanlapa Natedungta
Organization :
King Mongkut's University of Technology North Bangkok. Faculty of Applied Science
Organization :
King Mongkut's University of Technology North Bangkok. Faculty of Applied Science
Email :
walaiporn.o@sci.kmutnb.ac.th
ThaSH:
Nanogels
ThaSH:
Glutaral
Abstract:
This research is focused on preparation of glutaraldehyde (GA)-crosslinked gelatin hydrogel for application in controlled drug release system. Effect of GA concentration and gelation temperature were investigated. The optimum gelation temperature was found to be 40 degrees. The properties of the gelatin hydrogel depend on the presence of GA quantity. Increasing GA concentration caused increments in gel fraction, whereas porosity and swelling percentage decreased. Result obtained from scanning electron microscopy (SEM) showed that the greater amount of GA led to smaller pore size, hence affecting the mechanical property of hydrogel. The release of model drug, hydroquinone monosulfonate, from gelatin hydrogels was studied in pH 7.4 phosphate buffer and pH 4.5 acetate buffer solutions. The result showed that rate of drug release from the hydrogels was not significantly different for both pH solutions but influenced by GA concentration. The gelatin hydrogel with a higher crosslinking level resulted in a slow release rate of drug due to small porous structure of gelatin hydrogel.
King Mongkut's University of Technology North Bangkok. Central Library
Address:
BANGKOK
Email:
library@kmutnb.ac.th
Created:
2020
Modified:
2024-10-21
Issued:
2024-10-21
บทความ/Article
application/pdf
BibliograpyCitation :
In the Chemical Society of Thailand under the Patronage of Professor Dr. HRH Princess Chulabhorn in association, Thammasat University Faculty of Science and Technology. The Pure and Applied Chemistry International Conference 2020 (PACCON 2020) (PC167-172). Bangkok : Thammasat University
eng
©copyrights King Mongkut's University of Technology North Bangkok
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ใช้เวลา
0.029797 วินาที
Wanlapa Natedungta
| Title | Contributor | Type |
|---|---|---|
| Investigation of gelatin hydrogel gelation for drug release system
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Wanlapa Natedungta;Walaiporn Prissanaroon-Ouajai | บทความ/Article |
Walaiporn Prissanaroon-Ouajai
| Title | Contributor | Type |
|---|---|---|
| Evaluation of the possibility for using polypropylene/graphene composite as bipolar plate material instead of polypropylene/graphite composite
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Kannika Onyu;Rungsima Yeetsorn;Fowler, Miclael;Yu, Aiping;Jun, Yun Seok;Chaiwat Prapainainar;Walaiporn Prissanaroon-Ouajai | บทความ/Article | |
| Investigation of gelatin hydrogel gelation for drug release system
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Wanlapa Natedungta;Walaiporn Prissanaroon-Ouajai | บทความ/Article | |
| Hydrogel composite of bacterial cellulose and polyacrylamide for application in drug delivery
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Walaiporn Prissanaroon-Ouajai;Wanida Phungpai;Palida Hanprasert | บทความ/Article |