Antioxidant capacity in serum after fungicides exposure in garlic farmers

Name: Kanittharin Tipubon

Organization : Chiang Mai University. Faculty of Medicine

Name: Churdsak Jaikang

Organization : Chiang Mai University. Faculty of Medicine

Email : Churdsak.j@cmu.ac.th

Name: Yutti Amornlertwatana

Organization : Chiang Mai University. Faculty of Medicine

Name: Rangsan Watcharakawin

Organization : Mae tuen Health promoting Hospital

Name: Parinya Panuwet

Organization : Emory University. Rollins School of Public Health

ThaSH: Fungicides

ThaSH: Spraying and dusting residues in agriculture

ThaSH: Antioxidant

Abstract: Funigcides are widely used to control several fungal diseases in garlic farms. Several animals and in vitro studies have demonstrated the toxic effects of fungicides via the production of free radicals. However, no evidence has yet been captured in humans. This study aimed to determine the total antioxidant capacity (TAC) in the serum of garlic farmers who exposed to fungicides using 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid, ABTS) and ferric reducing ability of power (FRAP) assays. Blood samples were collected from the farmers who applied fungicides (n = 48) and the control subjects (n = 40). The average values of the ABTS assay of farmers and the control subjects were 117 + 9.09 and 98.79-5.12 mu mol Trolox Eq/L, respectively. Whereas, the FRAP values of farmers and the control subjects were 251.04 + 49.83 and 440 + 55.89 mu mol FeSO4 Eq/L, respectively. The TAC values of the farmers observed from the ABTS and the FRAP assays were significantly different than the control subjects (Mann winey U test, p < 0.0001). The results indicate that exposure to fungicides likely results in the generation of free radicals that induce oxidative stress in the garlic farmers. More research is needed to elucidate the health endpoints associated with this effect.

King Mongkut's University of Technology North Bangkok. Central Library

Address: BANGKOK

Email: library@kmutnb.ac.th

Created: 2020

Modified: 2023-12-15

Issued: 2023-12-15

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BibliograpyCitation : In the Chemical Society of Thailand under the Patronage of Professor Dr. HRH Princess Chulabhorn in association, Thammasat University Faculty of Science and Technology. The Pure and Applied Chemistry International Conference 2020 (PACCON 2020) (CB43-47). Bangkok : Thammasat University

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