แจ้งเอกสารไม่ครบถ้วน, ไม่ตรงกับชื่อเรื่อง หรือมีข้อผิดพลาดเกี่ยวกับเอกสาร ติดต่อที่นี่ ==>
หากไม่มีอีเมลผู้รับให้กรอก thailis-noc@uni.net.th
หากไม่มีอีเมลผู้รับให้กรอก thailis-noc@uni.net.th
Theeraphol Jatuponwiphat. Reconstruction of core iron-associated protein network of pasteurella multocida using comparative genome-scale analysis. Master's Degree(Biology). Kasetsart University. Office of the University Library. : Kasetsart University, 2017.
Reconstruction of core iron-associated protein network of pasteurella multocida using comparative genome-scale analysis
Name: Theeraphol Jatuponwiphat
Classification :.LCCS: QR82.P25
LCSH:
Pasteurella multocida
LCSH:
Genomes
Abstract:
Pasteurella multocida is a respiratory pathogenic bacterium that causes a wide range of diseases in animals and human via canine and feline scratches and bites. High-throughput sequencing and bioinformatics assisted the completion of fourteen P. multocida genomes obtained from various animal hosts. These genomes have been publicly available on GenBank database. However, information on comparative genomics on iron-associated protein-protein interaction (PPI) networks are poorly studied. Particularly, iron-associated PPI network of P. multocida strains among different animal hosts remains largely unknown. Therefore, this study is to identify iron-associated genes in the core genomes of P. multocida with overall aim at constructing functional modules related to virulence using genome-scale network analysis. Initially, the complete genome sequences of P. multocida were retrieved for gene prediction and core genome annotation. Directing from core genome, the functional classification was then performed in P. multocida. Iron-associated genes, which may involve in iron transport and metabolism, were classified and used to construct iron-associated PPI network. The constructed iron-associated PPI network was finally used for identification of functional module related to virulence in P. multocida. Our results showed that twelve modules were identified which are classified into seven ironassociated transport modules and five iron-associated metabolism modules, respectively. Furthermore, hemBNLH, yfeABC and ccmC genes were identified related to virulence in P. multocida. This finding information can lead to a better understanding of the pathway evolution regarding adaptation and pathogenicity of this bacterium. Our study has an impact on veterinary science and agriculture as pertaining to the rational identification of pathogen-specific drug targets and vaccine with pharmaceutical interest.
Kasetsart University. Office of the University Library
Address:
Bangkok
Email:
tdckulib@ku.ac.th
Name: Wanwipa Vongsangnak
Role:
Thesis Advisor
Name: Teerasak E-kobon
Role:
Thesis Co-Advisor
Created:
2017
Modified:
2023-06-30
Issued:
2023-06-30
วิทยานิพนธ์/Thesis
application/pdf
URL: https://kasetsart.idm.oclc.org/login?url=https://www.lib.ku.ac.th/KUthesis/2560/theeraphol-jat-all.pdf
CallNumber:
QR82.P25.T44
eng
DegreeName: Master of Science
Level: Master's Degree
Descipline: Biology
Grantor: Kasetsart University
©copyrights Kasetsart University
RightsAccess:
ใช้เวลา
0.025755 วินาที
Theeraphol Jatuponwiphat
| Title | Contributor | Type |
|---|---|---|
| Reconstruction of core iron-associated protein network of pasteurella multocida using comparative genome-scale analysis
มหาวิทยาลัยเกษตรศาสตร์ Theeraphol Jatuponwiphat | Wanwipa Vongsangnak Teerasak E-kobon | วิทยานิพนธ์/Thesis |
| Dissecting metabolic behavior of limosilactobacillus reuteri KUB-AC5 through genome and transcriptome data integration
มหาวิทยาลัยเกษตรศาสตร์ Theeraphol Jatuponwiphat | Wanwipa Vongsangnak | วิทยานิพนธ์/Thesis |
Wanwipa Vongsangnak
| Title | Creator | Type and Date Create |
|---|---|---|
| Functional annotation of metabolic transporters in aspergillus oryzae at a genome-scale
มหาวิทยาลัยเกษตรศาสตร์ Wanwipa Vongsangnak ;Wut Taksintum | Nachon Raethong | วิทยานิพนธ์/Thesis |
| Reconstruction of core iron-associated protein network of pasteurella multocida using comparative genome-scale analysis
มหาวิทยาลัยเกษตรศาสตร์ Wanwipa Vongsangnak ;Teerasak E-kobon | Theeraphol Jatuponwiphat | วิทยานิพนธ์/Thesis |
| Genome sequencing and annotation of limosilactobacillus fermentum KUB-D18 and Its comparison with other strains
มหาวิทยาลัยเกษตรศาสตร์ Wanwipa Vongsangnak | Panpaporn Phujumpa | วิทยานิพนธ์/Thesis |
| Transcriptome profiling of Cordyceps militaris under light and developmental stages
มหาวิทยาลัยเกษตรศาสตร์ Wanwipa Vongsangnak | Roypim Thananusak | วิทยานิพนธ์/Thesis |
| Integrative analysis of phenotypic traits and transcriptomes between mucor circinelloides strains for lipid production
มหาวิทยาลัยเกษตรศาสตร์ Wanwipa Vongsangnak ;Kobkul Laoteng | Li, Fanyue | วิทยานิพนธ์/Thesis |
Teerasak E-kobon