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Krongkaew Navakul. Nanocarbon and polymer composite biosensors for electrochemical determination of influenza A and Dengue Viruses. Doctoral Degree(Chemistry). Kasetsart University. Office of the University Library. : Kasetsart University, 2016.
Nanocarbon and polymer composite biosensors for electrochemical determination of influenza A and Dengue Viruses
Name: Krongkaew Navakul
Classification :.LCCS: TA418.9.N35
LCSH:
Carbon nanotubes
LCSH:
Biosensors
LCSH:
Electrochemistry
LCSH:
Influenza A virus
LCSH:
Dengue viruses
Abstract:
In the present work, we create a new biosensor with specific test for rapid, sensitive, inexpensive virus diagnostic. We also proposed that classification of viruses including measure the amount of viruses that can be investigated by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The electrochemical detection of virus was based on recognition-induced interaction of the surface charge. The modified gold electrode used as a biosensor which made of a polymer matrix reinforced with nanostructured carbon materials (e.g. carbon nanotubes and graphene) called polymer matrix composites (PMCs). According to the zeta potential measurement, the composites have negative charge while the virus particles have positive charge. So virus can interact with PMC and form active sites. After virus removal the active sites can be used to recognize again. When the electrode active sites are blocked again the resistance of the sensitive layer will increase in term of charge transfer resistance (Rct) of circuit analog. Hence the amount of virus determination. This biosensor shows high stability over time and can be used to determine virus qualitatively and quantitatively. The linear dependence of Rct versus virus concentrations is hold in a wide concentration range from 1 to 2×103 pfu/mL of virus with detection limit of 0.12 pfu/mL. It is easy to prepare selective, high sensitive and low-cost biosensors for early stage screening of disease.
Kasetsart University. Office of the University Library
Address:
Bangkok
Email:
tdckulib@ku.ac.th
Name: Chak Sangma
Role:
Thesis Advisor
Name: Chompunuch Warakulwit
Role:
Thesis Co-Advisor
Name: Kiattawee Choowongkomon
Role:
Thesis Co-Advisor
Name: Paiboon Ngernmeesri
Role:
Thesis Co-Advisor
Created:
2016
Modified:
2023-06-09
Issued:
2023-06-09
วิทยานิพนธ์/Thesis
application/pdf
URL: https://kasetsart.idm.oclc.org/login?url=https://www.lib.ku.ac.th/KUthesis/2559/krongkaew-nav-all.pdf
CallNumber:
TA418.9.N35.K76
eng
DegreeName: Doctor of Philosophy
Level: Doctoral Degree
Descipline: Chemistry
Grantor: Kasetsart University
©copyrights Kasetsart University
RightsAccess:
ใช้เวลา
0.035027 วินาที
Krongkaew Navakul
| Title | Contributor | Type |
|---|---|---|
| Effect of antigenic site mutation on cell receptor binding of influenza A virus (H5N1) hemagglutinin
มหาวิทยาลัยเกษตรศาสตร์ Krongkaew Navakul | Chak Sangma Kiattawee Choowongmon Songwut Surimitr | วิทยานิพนธ์/Thesis |
| Nanocarbon and polymer composite biosensors for electrochemical determination of influenza A and Dengue Viruses
มหาวิทยาลัยเกษตรศาสตร์ Krongkaew Navakul | Chak Sangma Chompunuch Warakulwit Kiattawee Choowongkomon Paiboon Ngernmeesri | วิทยานิพนธ์/Thesis |
Chak Sangma
| Title | Creator | Type and Date Create |
|---|---|---|
| Study of the binding mechanisms of different receptors bound to influenza a hemagglutinins and neuraminidases
มหาวิทยาลัยเกษตรศาสตร์ Chak Sangma | Nathjanan Jongkon | วิทยานิพนธ์/Thesis |
| Nanocarbon and polymer composite biosensors for electrochemical determination of influenza A and Dengue Viruses
มหาวิทยาลัยเกษตรศาสตร์ Chak Sangma ;Chompunuch Warakulwit;Kiattawee Choowongkomon;Paiboon Ngernmeesri | Krongkaew Navakul | วิทยานิพนธ์/Thesis |
Chompunuch Warakulwit
Kiattawee Choowongkomon
Paiboon Ngernmeesri