Antioxidant activities of Carica papaya L Leaf extract for cosmetic use

Name: Pinyada Kerdpremwes

keyword: Carica Papaya L. Leaf

MeSH: Papaya leaf -- Extracts -- 301704

Classification :.DDC: e-Theses

; Antioxidant

MeSH: Antioxidants -- 301705

MeSH: Cosmetics -- 301706

MeSH: Stability -- 301707

LCSH: Papaya leaf -- Extracts -- 301704

LCSH: Antioxidants -- 301705

LCSH: Cosmetics -- 301706

LCSH: Stability -- 301707

Abstract: The leaves of Carica papaya L. are reported to possess natural antioxidants and are generally considered as agricultural waste in Thailand. This study aimed to extract and quantify the phenolic and flavonoid contents in C. papaya leaves as well as their bioactivities in order to utilize the C. papaya leaf extract in antiaging cosmetics. The ultrasonic-assisted extraction technique was used and the preliminary screening of solvents was conducted. Aqueous extract of C. papaya leaves exhibited the highest potential antioxidant activities compared to 60% ethanol, 95% ethanol, and glycerol solvents, which was selected for further study. Total phenolic and flavonoid contents were discovered at 125.12 ± 3.02 mg GAE/g and 53.26 ± 1.34 mg QE/g. Accordingly, the IC50 value of DPPH radical scavenging of the extract was 0.1909 ± 0.0018 mg/ml and FRAP reducing power amount was 21.70 ± 0.38 mg AAE/g. C. papaya leaves extract in a solution form was also prepared to be incorporated into the cosmetic product which was also determined for its antioxidant compounds and activities. The results showed the potential use of C. papaya leaves as a natural antioxidant in cosmetics. Antiaging facial serums containing 0.3% and 0.6% of C. papaya leaves liquid extract were prepared. The DPPH inhibition was initially obtained at 43.11 ± 0.95% and 93.38 ± 1.39% for that of 0.3% and 0.6% extract serum, respectively, and decreased during a one-month stability study in which the changes were about 3% - 10% compared with that of the beginning. However, the physical and bioactive properties of both formulations were considered cosmetically acceptable. Further studies on phytochemical constituents, quantitative analysis, standardization and long-term stability should be conducted for the cosmetic application.

Mae Fah Luang University. Learning Resources and Educational Media Center

Address: CHIANG RAI

Email: library@mfu.ac.th

Name: Ampa Jimtaisong

Role: Advisor

Created: 2022

Modified: 2023-05-10

Issued: 2023-05-10

วิทยานิพนธ์/Thesis

application/pdf

CallNumber: e-Theses

eng

DegreeName: Master of Science

Level: Master's Degree

Descipline: Cosmetic Science

Grantor: Mae Fah Luang University

©copyrights Mae Fah Luang University

ลำดับที่.	ชื่อแฟ้มข้อมูล	ขนาดแฟ้มข้อมูล	จำนวนเข้าถึง	วัน-เวลาเข้าถึงล่าสุด
1	136105.pdf	1.38 MB	21	2026-05-26 18:16:01

ใช้เวลา

0.034853 วินาที