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Thitiphan Chimsook. Antioxidant and cytotoxic activities of Dendrobium signatum. (). King Mongkut's University of Technology North Bangkok. Central Library. : , 2016.
Antioxidant and cytotoxic activities of Dendrobium signatum
Name: Thitiphan Chimsook
Organization :
Maejo University. Department of Chemistry. Faculty of Science
Email :
thitiphan.cs@gmail.com
keyword:
Antioxidant
LCSH:
Cell culture
LCSH:
Plant extracts
-- Therapeutic use
Abstract:
Dendrobium, a genus of orchid, was found to possess useful therapeutic activities
such as anticancer, antimicrobial and antioxidant. The phytochemical investigation of the
ethanolic extracts of Dendrobium signatum stems revealed the presence of carbohydrates,
coumarins, alkaloids, phytosterols, flavonoids and phenolic compounds. This study aimed to
evaluate the antioxidant and anticancer activities of the extract. The total phenolic contents of
the extract were assessed by Folin Ciocalteau method using gallic and tannic acids as the
calibration standards. The total phenolic content was found to be 1.23% for gallic acid and
1.03% for tannic acid, respectively. The antioxidant potential was measured by using DPPH
method and the extract showed significant antioxidant activity with an IC50 value of 72
μg/mL. Anticancer study of the extract was performed against two human cancer lines (HeLa
and MCF-7) using MTT assay. The results showed that the extract displayed weak anticancer
activity against MCF-7 cell lines with the IC50 value of 31.75 μg/mL, while it was inactive
against HeLa cells
King Mongkut's University of Technology North Bangkok. Central Library
Address:
BANGKOK
Email:
library@kmutnb.ac.th
Created:
2016
Modified:
2023-01-03
Issued:
2023-01-03
บทความ/Article
application/pdf
BibliograpyCitation :
In Chemical Society of Thailand under the Patronage of Professor Dr. HRH Princess Chulabhorn and Chulalongkorn University Faculty of science. Pure and Applied Chemistry International Conference (PACCON 2016) (pp.1003-1006). Bangkok : Chemical Society of Thailand under the Patronage of Professor Dr. HRH Princess Chulabhorn
eng
©copyrights King Mongkut's University of Technology North Bangkok
RightsAccess:
ใช้เวลา
0.017937 วินาที
Thitiphan Chimsook
| Title | Contributor | Type |
|---|---|---|
| Antioxidant and cytotoxic activities of Dendrobium signatum
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Thitiphan Chimsook | บทความ/Article | |
| Development of analytical method for analysis of tetrahydrocannabinol and cannabidiol in tea infusion by High Performance Liquid Chromatography
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Thoranin Yosbunruengsin;Thitiphan Chimsook;Anakhaorn Srisaipech;Supaporn Sangsrichan | บทความ/Article |