Siriwan Ruangsiri. Contact angle property of poly(amidoamine) dendrimer coating onto titanium surface. (). King Mongkut's University of Technology North Bangkok. Central Library. : , 2022.
Contact angle property of poly(amidoamine) dendrimer coating onto titanium surface
Abstract:
Bacterial adhesion and biofilm formation are the causes of infection and main reasons for implant failure. In
order to improve potential antimicrobial properties of such implantable devices, biocompatible chemical surface coating
has been proposed as a good alternative to local delivery of antibiotics. The use of dendrimer, a specific class of monodisperse macromolecules with polyfunctionality, for the design of coating to alter surface properties is of interest. In this study, we performed simple surface coating of the titanium with various concentrations of poly(amidoamine)
(PAMAM) dendrimer, and characterized contact angle of the coating. Titanium is the most widely used materials for
orthopedic and dental implants. Also, our goal was to remain for the simple and low-cost contact angle measurement technique with use of open-source computer software and a cellphone camera. Results stated that PAMAM dendrimer
surface groups affected the properties of titanium surface. Compared with the uncoated control, the resulting coating of PAMAM dendrimer reduced contact angles of titanium surface. Water contact angle of the surface was lowered with
increased concentrations of PAMAM dendrimer used (0.2-1.0 mM), and it was concentration-dependent. Lower contact angles indicated more hydrophilic surfaces. This strategy of coating could provide a potential application for the
prevention of implant infections and is of relevance for the control of biofilm formation
King Mongkut's University of Technology North Bangkok. Central Library
Address:
BANGKOK
Email:
library@kmutnb.ac.th
Created:
2022
Modified:
2022-11-23
Issued:
2022-11-23
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BibliograpyCitation :
In King Mongkut's Institute of Technology Ladkrabang. Pure and Applied Chemistry International Conference (PACCON 2022) (pp.621-624). Bangkok : King Mongkut's Institute of Technology Ladkrabang