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Supatsorn Chupong. Bio-based composite materials from polylactide/microcrystalline cellulose from rice bran residue and its used as transdermal patch by electrospinning technique. Master's Degree(Engineering Technology). Thammasat University. Thammasat University Library. : Thammasat University, 2018.
Bio-based composite materials from polylactide/microcrystalline cellulose from rice bran residue and its used as transdermal patch by electrospinning technique
Name: Supatsorn Chupong
keyword:
Microcrystalline cellulose
Abstract:
Microcrystalline cellulose (MCC) has been prepared from extraction of rice bran waste. The materials contain high crystalline contents, and can be used as valuable additive in various fields. This work aimed to determine optimum conditions for MCC extraction from de-fatted rice bran by alkaline treatment and bleaching process to produce rice bran cellulose (RBC). The crystalline structure was extracted to a form of MCC by acid hydrolysis. The results suggest that 2 main factors effecting the qualities of RBC are sedimentation time in the alkaline treatment and NaClO2 concentrations. The characteristic of MCC were investigated. The results revealed that the proper conditions are 24 h sedimentation time and 2 % (w/v) of NaClO2. The surface of the resulting high crystallinity MCC was subsequently modified by using hydrophobic agent, alkyl ketene dimer (AKD, to enhance its solubility in solvent and compatibility with other polymers. In addition, after modifying with AKD, the primary-modified MCC powder was further treated with glycidyl trimethyl ammonium chloride (GTMAC) to introduce positive charges on the celluloses surface. The modified MCC samples are soluble in chloroform solvent, which is suitable for solution mixing with PLA. The mixture solutions are applied in electrospinning technique to produce continuous composite nanofibers for potential use as transdermal pain patch. Effect of mixing ratios of modified MCC and PLA on property of the resulting nanofibers was determined by varying the contents of AKD-modified MCC (primary modification) from 10, 15 and 20% (w/w) and those of AKD-GTMAC modified MCC (secondary modification) from 15 and 20%. Properties of the electrospun composite nanofibers were examined, in terms of chemical structures, thermal and mechanical properties, and also skin irritation property. The results reveals that GTMAC can increase the positive charge on the celluloses surface, leading to formation of strong interaction and hence an increase in mechanical properties of the nanofibers. The 20 % MCC+GTMAC (w/w) composite nanofiber showed the highest tensile strength and high elongation at break. The nanofibers prepared from both primary and secondary modifications MCC do not affect to human skin, making the materials suitable for the proposed biomedical applications
Thammasat University. Thammasat University Library
Address:
BANGKOK
Email:
preserv@tu.ac.th
Name: Pakorn Opaprakasit
Role:
advisor
Created:
2018
Modified:
2565-09-27
Issued:
2022-09-27
วิทยานิพนธ์/Thesis
application/pdf
eng
DegreeName: Master of Engineering
Level: Master's Degree
Descipline: Engineering Technology
Grantor: Thammasat University
©copyrights Thammasat University
RightsAccess:
ใช้เวลา
0.034714 วินาที
Supatsorn Chupong
| Title | Contributor | Type |
|---|---|---|
| Optimization of extraction condition of microcrystalline cellulose from rice bran residue
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Supatsorn Chupong;Pakorn Opaprakasit;Kittiwut Kaseamwong | บทความ/Article | |
| Bio-based composite materials from polylactide/microcrystalline cellulose from rice bran residue and its used as transdermal patch by electrospinning technique
มหาวิทยาลัยธรรมศาสตร์ Supatsorn Chupong | Pakorn Opaprakasit | วิทยานิพนธ์/Thesis |
Pakorn Opaprakasit