แจ้งเอกสารไม่ครบถ้วน, ไม่ตรงกับชื่อเรื่อง หรือมีข้อผิดพลาดเกี่ยวกับเอกสาร ติดต่อที่นี่ ==>
หากไม่มีอีเมลผู้รับให้กรอก thailis-noc@uni.net.th
หากไม่มีอีเมลผู้รับให้กรอก thailis-noc@uni.net.th
Supakorn Rojananin. Antibody Immune Response Compared between Recombinant Viral Vector and mRNA Vaccines among Health Care Personnel Who Had Previously Received 2 Doses of Inactivated COVID-19 Vaccine. (). Mae Fah Luang University. Learning Resources and Educational Media Center. : , .
Antibody Immune Response Compared between Recombinant Viral Vector and mRNA Vaccines among Health Care Personnel Who Had Previously Received 2 Doses of Inactivated COVID-19 Vaccine
Name: Sangkae Chamnanvanakij
Address:
333 Moo1, Thasud, Muang, Chiang Rai 57100
Organization :
School of Medicine, Mae Fah Luang University
Email :
ask.library@mfu.ac.th
Name: Somprat Munjit
Name: Ubonwan Jaroonruangrit
Name: Supakorn Rojananin
keyword:
COVID-19 vaccine
ThaSH:
Medicine
ThaSH:
COVID-19 (Disease)
;
Pfizer
ThaSH:
Viral vaccines
ThaSH:
SARS (Disease)
ThaSH:
Medical personnel
Abstract:
Background: Currently, a booster dose of AstraZeneca or Pfizer vaccine was introduced to healthcare personnel who had previously received two doses of inactivated vaccine.
Objective: To compare immune response and rate of adverse reactions after the third dose of AstraZeneca or Pfizer vaccines among healthcare personnel who had already received two doses of inactivated vaccine. We also determined immune response in those who received 2 doses of AstraZeneca vaccine.
Methods: We conducted an observational study at the Mae Fah Luang University Medical Center Hospital. We recruited healthcare personnel who had received AstraZeneca or Pfizer vaccine after 2 doses of Sinovac or received 2 doses of AstraZeneca vaccine. Those who were immunocompromised or had a history of COVID-19 infection were excluded. Participants were divided into 3 groups: (1) Sinovac-Sinovac-AstraZeneca, (2) Sinovac-Sinovac-Pfizer and (3) AstraZeneca-AstraZeneca. Immunoassay for anti-SARS-CoV-2 Spike protein (S) were performed at 30-60 days after the last vaccination dose. Adverse reactions after the third dose of vaccination were collected by using a questionnaire. We performed Kruskal Wallis test to compare antibody titer levels among the 3 groups. Comparisons of adverse reactions between group 1 and group 2 were analyzed using Chi-square or Fisher Exact test for categorical data as appropriate.
Results: There were 50, 111 and 18 participants of group 1, 2 and 3, respectively. All exhibited high titer levels of anti-SARS-CoV-2-S. The average antibody titer levels were highest in group 2 (p < 0.001), following by group 1 and group 3, respectively. Participants of group 1 reported fever and headache more frequently than those of group 2 (p < 0.001).
Conclusion: Current vaccination regimens, booster AstraZeneca or Pfizer vaccine after two doses of inactivated vaccine and 2 doses of AstraZeneca are efficacious in producing immunity against SARS-CoV-2.
Mae Fah Luang University. Learning Resources and Educational Media Center
Address:
CHIANG RAI
Email:
library@mfu.ac.th
Modified:
2022-09-05
Issued:
2022-09-05
บทความ/Article
application/pdf
GMS Medicine Journal Vol. 2 No. 2 May August 2022 61-68
eng
©copyrights Mae Fah Luang University
RightsAccess:
ใช้เวลา
0.030688 วินาที
Sangkae Chamnanvanakij
| Title | Contributor | Type |
|---|---|---|
| Comparison of time to umbilical cord separation using 3 cord-care regimens : triple dye, alcohol and no antiseptic agent
จุฬาลงกรณ์มหาวิทยาลัย Sangkae Chamnanvanakij | Sungkom Jongpiputvanich Nirun Vanprapar | วิทยานิพนธ์/Thesis |
| Prevalence and Associated Factors of Underweight Status among Children Aged 2-4 Years at Child-Care Centers of Wiang Subdistrict, Chiang Khong District, Chiang Rai Province
มหาวิทยาลัยแม่ฟ้าหลวง Pakjira Wongpradid;Donhatai Jaturakhachendecha;Sangkae Chamnanvanakij | บทความ/Article | |
| Antibody Immune Response Compared between Recombinant Viral Vector and mRNA Vaccines among Health Care Personnel Who Had Previously Received 2 Doses of Inactivated COVID-19 Vaccine
มหาวิทยาลัยแม่ฟ้าหลวง Sangkae Chamnanvanakij;Somprat Munjit;Ubonwan Jaroonruangrit;Supakorn Rojananin | บทความ/Article |
Somprat Munjit
| Title | Contributor | Type |
|---|---|---|
| Antibody Immune Response Compared between Recombinant Viral Vector and mRNA Vaccines among Health Care Personnel Who Had Previously Received 2 Doses of Inactivated COVID-19 Vaccine
มหาวิทยาลัยแม่ฟ้าหลวง Sangkae Chamnanvanakij;Somprat Munjit;Ubonwan Jaroonruangrit;Supakorn Rojananin | บทความ/Article | |
| Impact of Type 2 Diabetes Mellitus on Severity and Outcomes of the Patients Admitted with COVID-19 Infection: A Case-Control Study
มหาวิทยาลัยแม่ฟ้าหลวง Kaset Chimplee;Peeradone Srichan;Wirawan Chimplee;Somprat Munjit | บทความ/Article |
Ubonwan Jaroonruangrit
| Title | Contributor | Type |
|---|---|---|
| Antibody Immune Response Compared between Recombinant Viral Vector and mRNA Vaccines among Health Care Personnel Who Had Previously Received 2 Doses of Inactivated COVID-19 Vaccine
มหาวิทยาลัยแม่ฟ้าหลวง Sangkae Chamnanvanakij;Somprat Munjit;Ubonwan Jaroonruangrit;Supakorn Rojananin | บทความ/Article |
Supakorn Rojananin
| Title | Contributor | Type |
|---|---|---|
| Antibody Immune Response Compared between Recombinant Viral Vector and mRNA Vaccines among Health Care Personnel Who Had Previously Received 2 Doses of Inactivated COVID-19 Vaccine
มหาวิทยาลัยแม่ฟ้าหลวง Sangkae Chamnanvanakij;Somprat Munjit;Ubonwan Jaroonruangrit;Supakorn Rojananin | บทความ/Article |