Computer simulation based on FEM of laser-induced thermotherapy in human layered skin-tissue

การจำลองโดยใช้คอมพิวเตอร์ช่วยด้วยวิธีไฟไนท์อิลิเมนต์สำหรับการบำบัดเขิงความร้อนด้วยเลเซอร์ในขั้นเนื้อเยื่อมนุษย์

Name: Patcharaporn Wongchadakul

keyword: Laser

; Computer simulation

; Bioheat equation

; Finite element

Abstract: In modern medical facilities, laser irradiation is used in many different ways for skin treatment and increasingly well-known tool in the fight against the signs of ageing. Up to now, laser is becoming more and more important in surgical and dermatologic applications. Laser irradiation is a technique that carries out by the penetration and light scattering in bio-tissue under laser radiation, which results in heating of comparatively larger volumes through the thermal conversion of the absorbed light energy. However, the resulting thermo-mechanics response of the skin to various therapeutic temperatures during laser irradiation is not well understood. Therefore, it is interesting to investigate on the laser- induced thermal effect in skin during laser radiation. In addition to aesthetically, laser technology is also used for cancer treatment. Skin cancer is the deadliest form of cancer if it is not detected at an early stage. It is caused by sun exposure and grows in an uncontrolled way, invading adjacent tissues and tissue far away from cancer cells. Consequently, it causes severe damage to its organism. Several methods, including conventional or alternative methods, are used for treatment ; additionally, some methods are invasive treatment methods, including surgery and chemotherapy. Recent advancements in technology and imaging now offer minimally invasive treatments known as thermal ablation or laser treatment. However, unwanted thermal energy can cause injury. Therefore, skin cancer treatment using lasers requires computer simulation for thermal prediction and reduces side effects from hyperthermal. In this study, heat transfer and thermal shrinkage analysis in human skin are investigated by finite element method with COMSOLTM Multiphysics software, the effects of physical parameters, namely, wavelength, laser intensity, irradiation time, laser beam area, tumor position and tumor absorptivity on distributions of temperature profile within human skin are systematically investigated. The obtained results represent the accurate phenomena to determine the temperature increase in the human skin due to laser energy absorption. The results allow a better understanding of the realistic situation of the interaction between laser and the human skin tissues in aesthetically dermatology treatment and cancer treatment

Thammasat University. Thammasat University Library

Address: BANGKOK

Email: preserv@tu.ac.th

Name: Phadungsak Ratanadecho

Role: advisor

Created: 2017

Modified: 2565-03-04

Issued: 2022-03-03

วิทยานิพนธ์/Thesis

application/pdf

DOI: 10.14457/TU.the.2017.1396

eng

DegreeName: Doctor of Philosophy

Level: Doctoral Degree

Descipline: Medical Engineering

Grantor: Thammasat University

©copyrights Thammasat University

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