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Parama Pratummas. The effects of synbiotic supplement on gut-brain axis in cigarette smokers. Doctoral Degree(Anti-Aging and Regenerative Science). Mae Fah Luang University. Learning Resources and Educational Media Center. : Mae Fah Luang University, 2021.
The effects of synbiotic supplement on gut-brain axis in cigarette smokers
Effects of synbiotic supplement on gut-brain axis in cigarette smokers
Name: Parama Pratummas
keyword:
Synbiotic
Classification :.NLM: WM290
Abstract:
The influences of smoking at the intestinal microbiome and organized environment have been appeared in distinctive arranged controlled and observational clinical trials in individuals. This research proposed the impact of synbiotic supplement on gut-brain axis in cigarette smokers in the realm of gut-associated parameters and brain work. We directed a single gathering, pre- and post-test study; thirteen participants. Subjects were allocated to synbiotic supplement containing three types of prebiotics and seven sorts of probiotics before lunch every day for eight weeks. We measured in gut-related biochemical parameters change and alternation in brain, which were FTND, craving scores for smoking, lactulose-mannitol ratio (LMR), 5-HIAA, quinolinic acid (QA) and lipopolysaccharide (LPS). The present outcomes indicated essentially decline in the scores of FTND (p = 0.0012) and also the scores of craving for smoke after intervention (p = 0.0001). In additions, gut permeability assessed through LMR considerably reduced after the treatment (p = 0.0174). Likewise, a rise in 5-HIAA (p = 0.006) for serotonergic pathway and a fall in QA (p = 0.0253) and LPS (p = 0.0557) for kynurenine pathway, which all linked the gut to the brain in a bidirectional way as the gut-brain axis in cigarette smokers. It can be concluded that synbiotic supplement affected on gut-brain axis in both gut-related parameters and brain work within new perspectives.
Mae Fah Luang University. Learning Resources and Educational Media Center
Address:
CHIANG RAI
Email:
library@mfu.ac.th
Role:
Advisor
Created:
2021
Modified:
2021-12-17
Issued:
2021-12-17
วิทยานิพนธ์/Thesis
application/pdf
CallNumber:
WM290 P222e 2020
eng
DegreeName: Doctor of Philosophy
Level: Doctoral Degree
Descipline: Anti-Aging and Regenerative Science
Grantor: Mae Fah Luang University
©copyrights Mae Fah Luang University
RightsAccess:
ใช้เวลา
0.031067 วินาที
Parama Pratummas
| Title | Contributor | Type |
|---|---|---|
| The effects of synbiotic supplement on gut-brain axis in cigarette smokers
มหาวิทยาลัยแม่ฟ้าหลวง Parama Pratummas | Phakkharawat Sittiprapaporn | วิทยานิพนธ์/Thesis |
| Static Fatigue Detection in Office Syndrome Using Semg and Machine Learning
มหาวิทยาลัยธุรกิจบัณฑิตย์ Parama Pratummas | Chaiyaporn Khemapatapan | วิทยานิพนธ์/Thesis |
Phakkharawat Sittiprapaporn