The study of histopathologic spectrum in 59 patients exhibiting clinical features of urticarial vasculitis

Name: Matthasuda Tantasanee

keyword: Urticarial vasculitis

LCSH: Vasculitis

; Compatible with urticarial vasculitis

LCSH: Skin diseases

; Non-vasculitis

; Atypical urticaria

; Leukocytoclastic vasculitis

Abstract: Background: Urticarial vasculitis is a variant of cutaneous vasculitis characterized by atypical urticarial lesions that have the classical histopathologic features of leukocytoclastic vasculitis. However, the histologic features of early UV often present with subtle evidences of vasculitis. Therefore, UV is possibly underdiagnosed. Primary objective: To study the histopathology in patients exhibiting clinical features of urticarial vasculitis Secondary objective: To study the differences of clinical features and laboratory findings in vasculitis patients and non-vasculitis patients Methods: The retrospective study reviewed histopathology, clinical records, laboratory findings, and course of diseases in patients diagnosed of urticarial vasculitis at Thammasat University Hospital, Pathum Thani and Phramongkutklao Hospital, Bangkok, Thailand from 2012 to 2017. Patients were divided into 3 groups as the follows: 1) urticarial vasculitis group, 2) compatible with urticarial vasculitis (CUV) group, and 3) non-vasculitis group by the histologic criteria. The differences of clinical, histopathologic and laboratory findings were studies between each group. Results: Fifty-nine patients were enrolled in the study. Fourteen patients (23.7%) showed direct evidences of vasculitis and were designated as urticarial vasculitis group. Twenty-three patients (39%) showed secondary changes of vasculitis and were designated as CUV group and 22 patients (37.2%) were diagnosis as non-vasculitis group. There was no statistic significant between the presence of painful lesions, systemic symptoms, response to antihistamine, and high level of ESR in UV and CUV group. Nevertheless, the differences in these factors was presented between the CUV group and non-vasculitis group. The presence of painful lesions, systemic symptoms, response to antihistamine, time to response to treatment, and high ESR level were different between vasculitis group and non-vasculitis group. Conclusions: Our study showed the diagnosis of UV can be made even minimal secondary changes in histopathologic of vasculitis are present. The presence of painful lesions, systemic symptoms and high ESR level can help the clinician for diagnosis of UV

Thammasat University. Thammasat University Library

Address: BANGKOK

Email: preserv@tu.ac.th

Name: Panlop Chakkavittumrong

Role: advisor

Created: 2016

Modified: 2021-05-31

Issued: 2021-05-31

วิทยานิพนธ์/Thesis

application/pdf

DOI: 10.14457/TU.the.2016.546

eng

DegreeName: Master of Science

Level: Master's Degree

Descipline: Dermatology

Grantor: Thammasat University

©copyrights Thammasat University

ลำดับที่.	ชื่อแฟ้มข้อมูล	ขนาดแฟ้มข้อมูล	จำนวนเข้าถึง	วัน-เวลาเข้าถึงล่าสุด
1	2546matthasuda.pdf	2.13 MB

ใช้เวลา

0.021314 วินาที