Abstract:
The purpose of this study was to compare the combined effect of ACEI treatment and increasing daily physical activity compared with ACEI treatment alone for 12 weeks on microalbuminuria in type 2 diabetic patients. One hundred twenty five diabetic patients with microalbuminuria, aged 46-73 years old, were enrolled. A purposive sampling was used in this study to divided patients into intervention group (n=61) and control group (n=64).Intervention group was increasing daily physical activity by walking at least 2000 steps from baseline and with ACEI treatment. Control group was on ACEI alone. Microalbuminuria was assessed pre and post study for both groups. After 12 weeks study program, the number of patients of patients with significantly improvement were more in intervention group (63.5%, 40 from 61 patients) than in control group (36.5%.23 from 64 patients). Subjects from intervention group demonstrated significant increase in the number of steps (2370 ± 1482 vs. 4004 ± 2204 steps/day). There was no change in the number of steps in control group before and after study. Fasting blood glucose and HbA1c are not difference in both groups. This suggest that increasing daily physical activity by walking combined with ACEI treatments may be more effective in improving microalbuminuria in type 2 diabetic patients than ACEI treatment alone.