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Wanvimol Pasanphan. DOTA-BBN peptide conjugated water-soluble chitosan nanoparticles for a green synthesis of gold nanoplatform as a potential targeting radiopharmaceuticals. (). King Mongkut's University of Technology North Bangkok. Central Library. : , 2016.
DOTA-BBN peptide conjugated water-soluble chitosan nanoparticles for a green synthesis of gold nanoplatform as a potential targeting radiopharmaceuticals
Name: Theeranan Tangthong
Organization :
Kasetsart University. Faculty of Science
Name: Wanvimol Pasanphan
Organization :
Kasetsart University. Faculty of Science
Email :
wanvimol.p@ku.ac.th
keyword:
Water-soluble chitosan nanoparticle
LCSH:
Radiopharmaceuticals
Abstract:
The research aims to prepare water-soluble chitosan nanoparticle (WSCS NPs) and
conjugate it with LyslLys3(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid)-
Bombesin 1-14 (DOTA-BBN) peptide. The conjugated NPs were characterized using FT-IR,
SEM-EDX, XPS, TEM and Zetasizer. The WSCS-DOTA-BBN NPs exhibited spherical
shape with neutral surface charge. The particle size of WSCS and WSCS-DOTA-BBN NPs
were 12 ± 2 and 85 ± 11 nm and the hydrodynamic diameters were 175 and 192 nm,
respectively. A model non-radioactive AuNPs were then prepared using HAuCl4 and WSCSDOTA-
BBN NPs. AuNPs production was determined using UV-vis, SAXS, TEM and
Zetasizer. The sample solution showed color change and UV-vis absorption peak at 564 nm
implied successful creation of AuNPs in the WSCS-DOTA-BBN NPs. AuNPs were spherical
with the particle size of 61 ± 1 nm. The hydrodynamic size of AuNPs in WSCS-DOTA-BBN
NPs was 86 ± 2 nm. This research showed that WSCS-DOTA-BBN NPs is capable to be
used as a novel green reducing, stabilizing and targeting agent for producing AuNPs and may
be further extended to create analogous radioactive AuNPs as radiopharmaceutical
nanocarrier.
King Mongkut's University of Technology North Bangkok. Central Library
Address:
BANGKOK
Email:
library@kmutnb.ac.th
Created:
2016
Modified:
2019-11-27
Issued:
2019-11-27
บทความ/Article
application/pdf
BibliograpyCitation :
In Chemical Society of Thailand under the Patronage of Professor Dr. HRH Princess Chulabhorn and Chulalongkorn University Faculty of science. Pure and Applied Chemistry International Conference (PACCON 2016) (pp.917-922). Bangkok : Chemical Society of Thailand under the Patronage of Professor Dr. HRH Princess Chulabhorn
eng
©copyrights King Mongkut's University of Technology North Bangkok
RightsAccess:
ใช้เวลา
0.019961 วินาที
Theeranan Tangthong
| Title | Contributor | Type |
|---|---|---|
| DOTA-BBN peptide conjugated water-soluble chitosan nanoparticles for a green synthesis of gold nanoplatform as a potential targeting radiopharmaceuticals
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Theeranan Tangthong;Wanvimol Pasanphan | บทความ/Article | |
| Peptide conjugated water-soluble chitosan for green synthesis of gold nanoparticles as radiopharmaceuticals
มหาวิทยาลัยเกษตรศาสตร์ Theeranan Tangthong | Wanvimol Pasanphan | วิทยานิพนธ์/Thesis |
Wanvimol Pasanphan
| Title | Contributor | Type |
|---|---|---|
| DOTA-BBN peptide conjugated water-soluble chitosan nanoparticles for a green synthesis of gold nanoplatform as a potential targeting radiopharmaceuticals
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Theeranan Tangthong;Wanvimol Pasanphan | บทความ/Article | |
| Bio-additive chitosan for surface functionalization and antioxidant compounding of value-added commodity polymer
จุฬาลงกรณ์มหาวิทยาลัย Wanvimol Pasanphan | Suwabun Chirachanchai | วิทยานิพนธ์/Thesis |