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Somsak Sirichai. High-throughput isocratic HPLC method for determination of four paraben preservatives in cosmetics using chromolith column. (). King Mongkut's University of Technology North Bangkok. Central Library. : , 2016.
High-throughput isocratic HPLC method for determination of four paraben preservatives in cosmetics using chromolith column
Name: Anupat Boonsathit
Organization :
Burapha University. Faculty of Science
Name: Somsak Sirichai
Organization :
Burapha University. Faculty of Science
Email :
sirichai@go.buu.ac.th
keyword:
Chromolith column
Abstract:
A method for simultaneous determination four paraben preservatives in cosmetics by
using fast isocratic high-performance liquid chromatography was developed. Methyl paraben
(MP), ethyl paraben (EP), propylparaben (PP), and butyl paraben (BP) were analyzed on a
Chromolith reversed-phase 18e column (50 mm x 4.6 mm) using isocratic elution with
acetonitrile and water (32:68 v/v), and the flow rate was set at 3.00 mL·min1. Under these
optimal conditions, all analyte peaks were baseline separated with a run time of 2 min. The
linearity ranges for calibration curves were 0.05-8.00 mg·L1 for MP and EP, 0.10-10.00
mg·L1 for PP, and 0.20-10.00 mg·L1 for BP with a R2 more than 0.9995 for all analytes. The
limits of detection (0.01-0.06 mg·L1) and quantification (0.03-0.18 mg·L1) for the analytes
were obtained. The purposed method was successfully applied to determine the paraben
preservatives in cosmetic samples. The cosmetic samples were prepared by ultrasonic
extraction using acetonitrile with recoveries ranging from 96-105%.
King Mongkut's University of Technology North Bangkok. Central Library
Address:
BANGKOK
Email:
library@kmutnb.ac.th
Created:
2016
Modified:
2562-10-07
Issued:
2019-10-07
บทความ/Article
application/pdf
BibliograpyCitation :
In Chemical Society of Thailand under the Patronage of Professor Dr. HRH Princess Chulabhorn and Chulalongkorn University Faculty of science. Pure and Applied Chemistry International Conference (PACCON 2016) (pp.54-59). Bangkok : Chemical Society of Thailand under the Patronage of Professor Dr. HRH Princess Chulabhorn
eng
©copyrights King Mongkut's University of Technology North Bangkok
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ใช้เวลา
0.031275 วินาที
Anupat Boonsathit
| Title | Contributor | Type |
|---|---|---|
| High-throughput isocratic HPLC method for determination of four paraben preservatives in cosmetics using chromolith column
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Anupat Boonsathit;Somsak Sirichai | บทความ/Article |
Somsak Sirichai
| Title | Contributor | Type |
|---|---|---|
| Effect of solvent strength on the chromatographic behavior of certain phenolic compounds in reversed phase high performance liquid chromatography
จุฬาลงกรณ์มหาวิทยาลัย Somsak Sirichai | Vithaya Ruangpornvisuti Surapote Wongyai | วิทยานิพนธ์/Thesis |
| Fast electrophoresis chip analysis of ciprofloxacin and enrofloxacin in pharmaceutical formulations
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Somsak Sirichai;Khajadpai Thipyapong | บทความ/Article | |
| High-throughput isocratic HPLC method for determination of four paraben preservatives in cosmetics using chromolith column
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Anupat Boonsathit;Somsak Sirichai | บทความ/Article |