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Anintita Boonyawat. Exploring distribution of pathogenic gut microbiota in colorectal cancer subjects using quantitative PCR. Master's Degree(Biosciences). Mae Fah Luang University. Learning Resources and Educational Media Center. : , 2018.
Exploring distribution of pathogenic gut microbiota in colorectal cancer subjects using quantitative PCR
Name: Anintita Boonyawat
Address:
333 Moo1, Thasud, Muang, Chiang Rai 57100
Organization :
Mae Fah Luang University. School of Science. Biosciences
Email :
ask.library@mfu.ac.th
keyword:
Gut microbiota
LCSH:
Gastrointestinal system
-- Microbiology
Classification :.LCCS: QP156
LCSH:
Gastrointestinal system
-- Diseases
LCSH:
Microbiota
LCSH:
Intestines
-- microbiology
LCSH:
Systems biology
Abstract:
Colorectal cancer (CRC) is the third most prevalent cancer in the world. Recently, the human microbiota has been shown to define their role and have a dynamic impact on the human health. The etiology of CRC is increasing evidence that human microbial dysbiosis contributes to CRC development, particularly the pathogenic bacteria. However, the relationship between human microbiota and CRC is still under-explored. This study was aimed to quantify and compare the composition of pathogenic bacteria which might involving to CRC in different groups of subjects. Quantitative PCR (qPCR) was used to analyze and compare human microbiota composition from three different compartments including saliva, feces, and colonic tissue of three groups of the subject including 6 patients with colorectal cancer (CRC), 11 participants with adenomatous polyp (PO), and 21 normal participants (NO). The result indicate that the different compartments of the gastrointestinal tract (GI) was showed different of bacterial community. Salivary microbiota is differ from the microbiota of the intestinal lumen (feces and washes from colonic tissue). The most of pathogenic bacteria were high prevalence in the adenomatous polyp group. However, a significant difference of interested pathogenic bacteria was not observed. There are limitations to the study. Further study should explore the role of bacteria in the mechanisms involved in the development of CRC and increasing the size of the population in the study for more precision of experiment.
Mae Fah Luang University. Learning Resources and Educational Media Center
Address:
CHIANG RAI
Email:
library@mfu.ac.th
Name: Siam Popluechai
Role:
Advisor
Email :
ask.library@mfu.ac.th
Name: Art Hiranyakas
Role:
Co-Advisor
Email :
ask.library@mfu.ac.th
Created:
2018
Issued:
2562
Modified:
2019-09-03
Issued:
2019-09-03
วิทยานิพนธ์/Thesis
application/pdf
CallNumber:
Thesis QP156 A598e 2018
eng
DegreeName: Master of Science
Level: Master's Degree
Descipline: Biosciences
©copyrights Mae Fah Luang University
RightsAccess:
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0.022906 วินาที
Anintita Boonyawat
| Title | Contributor | Type |
|---|---|---|
| Exploring distribution of pathogenic gut microbiota in colorectal cancer subjects using quantitative PCR
มหาวิทยาลัยแม่ฟ้าหลวง Anintita Boonyawat | Siam Popluechai Art Hiranyakas | วิทยานิพนธ์/Thesis |
Siam Popluechai
Art Hiranyakas
| Title | Creator | Type and Date Create |
|---|---|---|
| Investigation of butyrate producing microbiota in Thai colorectal cancer subjects
มหาวิทยาลัยแม่ฟ้าหลวง Siam Popluechai;Art Hiranyakas | Nantinee Moontan | วิทยานิพนธ์/Thesis |
| Exploring distribution of pathogenic gut microbiota in colorectal cancer subjects using quantitative PCR
มหาวิทยาลัยแม่ฟ้าหลวง Siam Popluechai;Art Hiranyakas | Anintita Boonyawat | วิทยานิพนธ์/Thesis |