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Khajadpai Thipyapong. Fast electrophoresis chip analysis of ciprofloxacin and enrofloxacin in pharmaceutical formulations. (). King Mongkut's University of Technology North Bangkok. Central Library. : , 2017.
Fast electrophoresis chip analysis of ciprofloxacin and enrofloxacin in pharmaceutical formulations
Name: Somsak Sirichai
Organization :
Burapha University. Faculty of Science
Email :
sirichai@go.buu.ac.th
Name: Khajadpai Thipyapong
Organization :
Burapha University. Faculty of Science
keyword:
Electrophoresis chip
LCSH:
Ciprofloxacin
Abstract:
Electrophoresis chip with fluorescence detection was developed for highly efficient
separation and determination of ciprofloxacin and enrofloxacin in pharmaceutical
formulation. The determination of ciprofloxacin and enrofloxacin in pharmaceutical
formulations is very important with regard to the standardization and to the monitoring of the
stability of such formulation. The influence of two analytical parameters, the pH and
concentration of buffer, were studied. Under an optimum condition (20 mM phosphate buffer,
pH 2.2), a mixture containing ciprofloxacin was completely within 30 s. A good linear fit
curve with the concentration of 2.0 to 20.0 mg/L for ciprofloxacin and enrofloxacin was
obtained, with regression coefficients of 0.9985 and 0.9984, respectively. The LODs and
LOQs of both analytes were 0.50 and 2.0 mg/L, respectively. Precisions in terms of relative
standard deviation of the migration and peak area of ciprofloxacin and enrofloxacin were less
than 1.0% and 3.0%, respectively. The range of mean recoveries of ciprofloxacin and
enrofloxacin by the proposed method was 93-98%, and 90-95%, respectively. The proposed
method proved to be rapid, and reliable for the determination of ciprofloxacin and
enrofloxacin.
King Mongkut's University of Technology North Bangkok. Central Library
Address:
BANGKOK
Email:
library@kmutnb.ac.th
Created:
2017
Modified:
2562-07-23
Issued:
2019-07-23
บทความ/Article
application/pdf
BibliograpyCitation :
In Chemical Society of Thailand under the Patronage of Her Royal Hghness Princess Chulabhorn Mahidol and King Mongkut's University of Technology North Bangkok Faculty of Applied Science. Pure and Applied Chemistry International Conference (PACCON 2017) (pp.113-118). Bangkok : Chemical Society of Thailand under the Patronage of Her Royal Hghness Princess Chulabhorn Mahidol
eng
©copyrights King Mongkut's University of Technology North Bangkok
RightsAccess:
ใช้เวลา
0.02968 วินาที
Somsak Sirichai
| Title | Contributor | Type |
|---|---|---|
| Effect of solvent strength on the chromatographic behavior of certain phenolic compounds in reversed phase high performance liquid chromatography
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| Fast electrophoresis chip analysis of ciprofloxacin and enrofloxacin in pharmaceutical formulations
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Somsak Sirichai;Khajadpai Thipyapong | บทความ/Article | |
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| Fast electrophoresis chip analysis of ciprofloxacin and enrofloxacin in pharmaceutical formulations
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Somsak Sirichai;Khajadpai Thipyapong | บทความ/Article |