Thaksaporn Kridsuriya. Efficacy and safety of non-invasive abdominal tightening with high-intensity focused ultrasound (HIFU) in postnatal case : \b the clinical trial study. Master's Degree(Dermatology). Mae Fah Luang University . : Mae Fah Luang University , 2017.
Efficacy and safety of non-invasive abdominal tightening with high-intensity focused ultrasound (HIFU) in postnatal case : b the clinical trial study
Abstract:
Skin laxity is an aesthetic problem that occurs between the ages of 35 and 40 years. Problems with skin laxity and quality also start to appear in younger people as a consequence of pregnancy or sudden weight loss. High Intensity Focused Ultrasound or HIFU is now a one of effective non-surgical procedure to treat mild-to-moderate skin laxity. In this study, we sought to determine the clinical efficacy and safety of High Intensity focused ultrasound for abdominal tightening in postnatal woman and follow up at 4, 8 and 12 weeks. To study effect and safety of High Intensity Focused Ultrasound to treat abdominal skin laxity. Eleven postnatal participants with mild to moderate abdominal skin laxity were enrolled in this clinical trial study. The participants were treated with HIFU at lower abdominal area compare with control group. Three blinded independent dermatologists assessed results using standardized photographs according to the Global Aesthetic Improvement Scale (GAIS) evaluated paired pre- and post-treatment (week 4, 8 and 12). Skin elasticity was measured before and after treatment (week 4, 8, 12) using a Cutometer (MPA580, Courage and Khazaka®, Cologne, Germany). Participants also completed self-assessments using GAIS. Subjects rated their pain on a numeric rating scale (NRS) immediately, 4 weeks, 8 weeks and 12 weeks after treatment. Skin elasticity measured via a Cutometer was significantly improved immediately after treatment compare with control group (p = 0.006) and also significantly improved immediately after treatment within group compare with baseline (p =0.003). Physicians GAIS showed clinical improvement 4 weeks after treatment (mean ± SD: 2.94 ± 0.25). According to Subjects GAIS also showed clinical improvement immediately after treatment (mean ± SD: 3.27 ± 0.65). Immediately after treatment the mean NRS score was 5.36 ± 2.54, but no pain was reported at weeks 4, 8 and 12 after treatment. No permanent adverse effects were observed during the follow-up period. In case of postnatal abdominal tightening. HIFU appears to be a safe and effective treatment modality to improve skin elasticity for dermal and subdermal tightening.