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Paramee Tepsatian. Preparation of chitosan nanoparticle containing Oolong tea extract for cosmetic application. Master's Degree(Cosmetic Science). Mae Fah Luang University . : Mae Fah Luang University , 2017.
Preparation of chitosan nanoparticle containing Oolong tea extract for cosmetic application
Name: Paramee Tepsatian
Organization :
Mae Fah Luang University
keyword:
Oolong tea
LCSH:
Chitosan
-- therapeutic use
Classification :.LCCS: WA744
LCSH:
Cosmetics
LCSH:
Plant Preparations
Abstract:
Oolong tea is becoming increasingly popular across the world because of its antioxidant properties and taste. The goal of this study was to investigate the possibility of producing chitosan nanoparticles loaded with Oolong tea extract for cosmetic applications.
First, Oolong tea was extracted at various extraction conditions including soaking and stirring for 3, 7, 5, and 10 minutes in hot water (80 °C). The antioxidant activities of aqueous extract were evaluated by using DPPH radical scavenging, ABTS radical scavenging and ferric reducing power assays. The extract derived from 5 minutes of stirring exhibited the highest DPPH radical scavenging (37.52 mM AAE/g extract), ABTS radical scavenging (29.70 mM TE/g extract) and ferric reducing power (16.77 mM Fe2+/g extract). Epigallocatechin (173.67 µg/mL), epigallocatechin gallate (45.33 µg/mL), and caffeine (39.41 µg/mL) were found as major compound by HPLC analysis. In order to enhance the stability and penetration of the extract, chitosan (CS) tripolyphosphate (TPP) nanoparticles were developed.
Tea extract-loaded CS-TPP nanoparticles were successfully prepared by the ionotropic gelation method and the ratio of chitosan, TPP and the extract of 1:6:3 resulted in high entrapment efficiency (67.39 %), small particle size (429.4 nm) with narrow distribution (PDI 0.083) and zeta potential values of 40.6 mV. CS-TPP nanoparticles enhanced the stability of Oolong tea extract when stored at an ambient temperature and 45˚C. Furthermore, Oolong tea nanoparticles gel showed a significantly enhanced more elasticity value (12.81 %) than Oolong tea gel (5.69 %) and placebo gel (-0.11 %). Both Oolong tea nanoparticles gel and Oolong tea gel enhanced more skin moisture value (17.93 %) than that of placebo gel (10.44 %). The results indicated that CS-TPP nanoparticle can enhanced skin elasticity but not effect on skin moisture.
Mae Fah Luang University
Address:
CHIANG RAI
Email:
library@mfu.ac.th
Name: Nisakorn Saewan
Role:
Advisor
Created:
2017
Issued:
2561
Modified:
2018-09-11
Issued:
2018-09-11
วิทยานิพนธ์/Thesis
application/pdf
CallNumber:
Thesis WA744 P222p 2017
eng
DegreeName: Master of Science
Level: Master's Degree
Descipline: Cosmetic Science
Grantor: Mae Fah Luang University
ใช้เวลา
0.037605 วินาที
Paramee Tepsatian
| Title | Contributor | Type |
|---|---|---|
| Preparation of chitosan nanoparticle containing Oolong tea extract for cosmetic application
มหาวิทยาลัยแม่ฟ้าหลวง Paramee Tepsatian | Nisakorn Saewan, Ph. D. | วิทยานิพนธ์/Thesis |
Nisakorn Saewan
| Title | Creator | Type and Date Create |
|---|---|---|
| Anti-Aging potential of pigmented rice and their stem cell extracts
มหาวิทยาลัยแม่ฟ้าหลวง Nisakorn Saewan, Ph. D. | Wannisa Vichit | วิทยานิพนธ์/Thesis |
| Preparation of chitosan nanoparticle containing Oolong tea extract for cosmetic application
มหาวิทยาลัยแม่ฟ้าหลวง Nisakorn Saewan, Ph. D. | Paramee Tepsatian | วิทยานิพนธ์/Thesis |
| Encapsulation of ferulic acid in phosphorylated rice starch
มหาวิทยาลัยแม่ฟ้าหลวง Nisakorn Saewan;Nont Thitilertdecha | Jittraporn Pueknang | วิทยานิพนธ์/Thesis |
| Anti-hair loss efficacy of coffee berry extract
มหาวิทยาลัยแม่ฟ้าหลวง Nisakorn Saewan | Thanon Prinyarux | วิทยานิพนธ์/Thesis |
| Anti-Hair Loss properties of resveratrol rich callus extract
มหาวิทยาลัยแม่ฟ้าหลวง Nisakorn Saewan | Wannisa Vichit | วิทยานิพนธ์/Thesis |