Comparative lipid-lowering effects of combination of oat beta-glucan and policosanol versus oat-glucan alone in a population of hypercholesterolemin men and women

Name: Chanida Bhanubandh Na Ayubhya

Organization : Mae Fah Luang University

keyword: Lipid-lowering

LCSH: Hypercholesterolemia -- complications

Classification :.LCCS: WB405

LCSH: Cholesterol

Abstract: This study aimed to compare the cholesterol-lowering effects of the combination of Oat Beta-Glucan and Policosanol versus Oat Beta-Glucan alone in a population of hypercholesterolemia men and women. 60 participants with LDL-C 130-190 mg/dL had divided into two groups by randomization. The experimental group had been received Oat Beta-glucan 3 g/d along with Policosanol 20 mg/d as they split into two meals a day for 12 weeks. The control group had been received Oat Beta-glucan 3 g/d along with Placebo as they splitted into two meals a day for 12 weeks. Both groups had tendency of LDL-C level to be decreased from all four periods of times. When comparing to LDL-C level within the same group, it was found that in the experimental group, the LDL-C had decreased significantly since the 4th week onwards as p=0.001, p<0.001, and p<0.001, respectively. The controlled group had decreased significantly since the 4th week onwards with p<0.001. On the other hand, when comparing to each periods between two groups, there were no statistically difference in all four periods. No significant reduction showed in the 12th week between both groups; the experimental group was -29.12 mg/dl (19.59%) versus the controlled group was -24.88 mg/dl (16.31%) (p=0.43). Consequently, the combination of the Oat Beta-Glucan and Policosanol was no more significant effective in lowering cholesterol than the Oat Beta-Glucan alone over 12 weeks in a population of hypercholesterolemia which is required further clinical research studies in longer intervention periods.

Mae Fah Luang University. The Learning Resources and Education Media Center

Address: Chiang Rai

Email: library@mfu.ac.th

Name: Karnt Wongsuphasawat

Role: Advisor

Created: 2015

Issued: 2016

Modified: 2020-04-20

Issued: 2016-12-01

วิทยานิพนธ์/Thesis

application/pdf

CallNumber: Thesis WB405 C456c 2015

eng

DegreeName: Master of Science

Level: Master's Degree

Descipline: Anti-Aging and Regenerative Medicine

Grantor: Mae Fah Luang University

©copyrights Mae Fah Luang University

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