Abstract:
The objectives of this research were to study 1) health related quality of life of patient with schizophrenia and substance use disorder in community, and 2) the relationship between selected factors including gender, age, type of substance, daily consumption of cigarettes and cup of coffee, negative and positive symptoms, social support, family relationship, and drug adherence with health related quality of life. A total of 160 persons with schizophrenia and substance use disorders, who sought treatment at outpatient department of Saraburi hospital, Sena Hospital, Tharuea hospital, Sam Khok hospital, and Somdet Chaopraya Institute of Psychiatry, were recruited according to the inclusion criteria. The research instruments were demographic questionnaire, substance use questionnaire, positive and negative syndrome scale, social support questionnaire, family relationship questionnaire, drug adherence questionnaire and SF-36. All instruments were tested for content validity. The six latter instruments had Cronbach's alpha coefficient reliability as of .96, .96, .90, .84, .86, and .94, respectively. Statistic techniques utilized in data analysis were Frequency, Percentage, Mean, Standard deviation, One-way Analysis of Variance (ANOVA) and Pearson's product moment correlation.Major finding of this study were as follows:1. Persons with schizophrenia and substance use disorders had score on health related quality of life by overall as well as all subscales (physical functioning domain, bodily pain domain, social functioning domain, limitations in usual role activities due to physical health problems domain, limitations in usual role activities due to emotional problems domain, mental health domain, vitality domain, and general health perception domain) in the good level (mean= 72.01, 85.63, 76.69, 75.19, 74.06, 72.60, 67.54, 65.96, and 63.95 respectively). 2. Scores on health related quality of life of persons who used difference types of substance were significantly different (F=3.96, p .05). Daily consumption cup of coffee, social support, family relationship, and drug adherence were significantly and positively related to health related quality of life (r=.19, .50, .45, and .56, respectively; p .05). In addition, positive symptoms and negative symptoms were significantly and negatively related to health related quality of life (r =-.46, and -.41, respectively; p = .05). Age, gender and daily consumption of cigarettes were not significantly related to health related quality of life.