Abstract:
This study was researched on the Effect of L-Carnitine Versus L-Carnitine and Niacin on
Lipid Profile in Dyslipidnemia Patient. Experimental model involved 43 volunteers divided into 3
groups, group 1 with placebo, group 2 with L-carnitine 3 g/day, and group 3 with L-carnitine 3 g/day
and niacin 250 mg/day for 4 weeks. Data collections on lipid profiles of volunteers taken only Lcarnitine
had shown that there was no difference in total cholesterol, triglyceride and HDL, but
significantly increase the level of LDL; 110.40±14.56 and 128±16.50 (p =0.001). It could be assumed
that volunteers were not dietary control. Volunteers who took L-carnitine with niacin had shown
significantly decrease in total cholesterol; 225.80±25.46 and 200.33±42.80 (p=0.015).
The conclusion is daily intake of L-carnitine 3 g/day could not only reduce lipid profile, but
could also increase LDL whereas daily intake of L-carnitine 3 g/day with niacin could reduce total
cholesterol.