Abstract:
The present thesis presents the invention of a 2-source Bio-impedance Analyzer for application in hemodialysis patients. The analyzer uses bogth direct and alternative current source to replace the conventional phase shift measurement so as to avoid measurement problem. The analyzer consists of 6 main parts: power supply, signal generator circuit, constant current circuit, voltage measurement circuit, processing circuit, and display. First, performance of the system was investigated in measuring pure resistor, pure capacitor, and resistor-capacitor parallel circuit as a model of tissue. It was found that the system could measure impedance and resistance in the range of 160~1000Ω and 200~1000Ω, respectively. The coefficient of determination of 0.999 was obtained. Second, the system was applied to measure in good health people comparing with the results obtained from Maltron Bioscan 916S. It was found that when the alternative current was applied to measure impedance a satisfactory result was obtained with a coefficient of determination of 0.979. However, when the directive current was applied to measure the resistance, reasonable results were obtained only when the test group were males who have a body mass index higher 20 kg/m². The coefficient of determination of 0.651 was obtained