Watcharee Prasertkulchai. Measurement of transverse relaxation time (T2) of iron by using 15T and 3T magnetic resonance imaging; a study in phantom model. Master's Degree(Radiological Technology ). Mahidol University. : Mahidol University, 2008.
Measurement of transverse relaxation time (T2) of iron by using 15T and 3T magnetic resonance imaging; a study in phantom model
Abstract:
Magnetic Resonance Imaging (MRI) is currently widely used as a diagnostic tool
in medicine. Iron concentration in different organs such as heart and liver can be used
to diagnose various diseases. The iron concentration in vivo can be measured by
estimating transverse relaxation times (T2) and comparing the values with known
different concentrations of iron in phantom model. This study was carried out to
compare results of iron concentration measurements from 1.5T and 3.0T MRI systems.
A General Electrics 1.5T and a Philips 3.0T MRI systems at AIMC center,
Ramathibodi hospital were used in this study. Clinically relevant iron concentrations
ranging from 0.3 mgFe to 45.3 mgFe were prepared in the phantom model.T2
calculation was based on spin echo method. Technical settings were TR = 2500 msec,
TE ranged from 6 msec to 126 msec, Field of view 350, matrix size 256 x 256 and
slice thickness 6 mm with slice gap 6 mm. The results showed T2 values ranged from
5.09 - 66.21 and 3.79 - 36.14 for 1.5T and 3.0T systems, respectively. Accuracy of
measurement in terms of percentage error was found between 0.4% to 24% and 3% to
23% for 1.5T and 3.0T systems, respectively. We conclude that T2 values and iron
concentration were related exponentially. Moreover, in clinically relevant iron
concentration level, T2 values obtained from 1.5T system were about 35% longer than
those from 3.0T system. Our study