Prapa Sodkokkruad. Comparison of proton MR spectroscopy between 15 T and 30 T. Master's Degree(Medical Physics ). Mahidol University. : Mahidol University, 2006.
Comparison of proton MR spectroscopy between 15 T and 30 T
Abstract:
Magnetic resonance spectroscopy (MRS) is widely available for clinical practice, particularly for brain applications, because it can provide information on metabolite of the interest region. In the past, MRS was performed at 1.5 T MR scanner, but now 3.0 T is widely used. The main advantage of higher field strength is the increase of the signal to noise ratio (SNR) and spectral resolution. To that end, this study performs the same 1H-MRS examination in the phantom by using Single voxel proton MR spectroscopy with PRESS sequence at both 1.5 T and 3.0 T MR scanner at Ramathibodi Hospital. Acquisition parameters were closely matched between field strength. The goals of SNR and spectral resolution between field strength and comparisons between coils at 3.0 T were made. The spectra at 3.0 T demonstrated about 14.06 60.63% improvement in SNR compared to 1.5 T at long TE (TE=70, 144, 288 msec) but spectra at short TE (40 msec) exhibited SNR at 3.0 T was lower than 1.5 T. At 3.0T, the SNR from quadrature mode in the Sense head coil was the highest. Expected gain in SNR is not fully improved according to the theory because of intrinsic and controllable factors. Spectral resolutions of spectra at 3.0 T were significant improved compared to 1.5 T. However, the increase of the magnetic field strength increase SNR and spectral resolution can lead to more accurate identification of each metabolite.