Korravarn Yodmai. Incidence and risk factors of preeclampsia in Ramathibodi Hospital . Master's Degree(Human Reproduction and Population Planning ). Mahidol University. : Mahidol University, 2007.
Incidence and risk factors of preeclampsia in Ramathibodi Hospital
Abstract:
The first part of this study is a historical cohort study with the objective to
determine the incidence of preeclampsia among nulliparous women who came to
register for the first time at the antenatal care booking unit Ramathibodi Hospital,
Thailand during 1 January – 30 December 2005. The second part is a case – control
study with the objective to determine risk factors of preeclampsia. During the study
period, there were 2,543 pregnant women who came to register for the first time. For
those who failed to follow up attempt to contact was done by mail or telephone.
Overall, 68.7 percentage of women who registered had known outcomes of pregnancy
(65.7% delivery, 3.1% abortion). Descriptive statistics were number and percentage.
Analytical statistics including odds ratio with 95% confidence intervals, chi – square
test, and logistic regression were used to determine risk and association of factors and
preeclampsia. SPSS/PC+ program was used for statistical analysis.
The results of the study showed that the incidence of preeclampsia was 4.9%
(3.4% mild preeclampsia and 1.5% severe preeclampsia). The case - control study
included 82 cases of preeclampsia and 82 cases of control. The controls were selected
from pregnant women who came to register on the same day just after the
preeclampsia cases. The significantly associated factors were maternal age more than
30 years old, occupation of house-wife, body mass index (BMI) at first ANC visit
more than 25 kg/m2, and mean gain weight of 0.5 kg/wk or more than (p < 0.05).
In conclusion, incidence of preeclampsia in Ramathibodi Hospital is
comparable to other studies. Risk factors of preeclampsia could be applied in
screening pregnant women and to advise them and prepare services to prevent and
treat risk of or development of preeclampsia.