Taddao Rungwongsri. Effect of casein phosphopeptide amorphous calcium phosphate paste versus fluoride gel on remineralization of enamel erosion with chlorinated water. Master's Degree(Pediatric Dentistry). Mahidol University. : Mahidol University, 2008.
Effect of casein phosphopeptide amorphous calcium phosphate paste versus fluoride gel on remineralization of enamel erosion with chlorinated water
Abstract:
Purpose: This study aims to evaluate the effect of fluoride toothpaste, fluoride
gel and CPP-ACP on rehardening and preventing enamel surfaces from eroion from
acidic water.
Methods: One-hundred specimens were randomly divided into 2 sets of
experiments in order to evaluate the effect of treatments before and after
demineralizaion. Fifty specimens were immersed in demineralizing solution
(chlorinated water pH 5.0) for 2 h. then divided into 5 groups (A to E; n=10). Group A
specimens were stored in artificial saliva for 22 h. Group B specimens were stored in
artificial saliva for 1 h. and then brushed with fluoride toothpaste for 15 s. They were
then soaked in toothpaste slurry (1:3 w/w) for 105 s. SnF2 gel was used for 120 s. for
group C specimens and CPP-ACP was used for 180 s. for group D specimens. Group E
specimens were applied with SnF2 gel for 120 s. and then CPP-ACP for 180 seconds.
The other fifty specimens were divided into 5 groups (F to J; n=10). Group F
specimens were stored in artificial saliva for 15 min. Group G specimens were stored in
artificial saliva for 15 min. and then brushed with fluoride toothpaste for 15 s., and
soaked in toothpaste slurry (1:3 w/w) for 105 s. SnF2 gel was used for 120 s. for group
H specimens and CPP-ACP was used for 180 s. for group I specimens. Group J
specimens were applied with SnF2 gel for 120 s., followed by CPP-ACP for 180 s. After
that, they were left in artificial saliva for 30 min. and immersed in demineralizing
solution for 2 h.
After these treatments, the specimens were kept in artificial saliva for 24 h. All
procedures were repeated everyday for 14 days. Microhardness testing was made
initially and after experiments.
Results: The SnF2 and CPP-ACP groups were found to give the highest enamel
surface microhardness when compared with the other groups (p<0.05). For pretreatment
groups, no significant difference among various products was found (p=0.09).
Comparison between treatment after erosion and before erosion showed a significant
difference between treatment before and after (p=0.00).
Conclusion: It was concluded that SnF2 or CPP-ACP were more effective only
in rehardening eroded enamel surfaces after chlorinated water exposure, and was
without preventive effect.