Kemiga Waraporn. Usefulness of computed tomographic imaging of the chest in evaluation pathologic cell type of primary lung cancer disease . Master's Degree(Radiological Science). Mahidol University. : Mahidol University, 2006.
Usefulness of computed tomographic imaging of the chest in evaluation pathologic cell type of primary lung cancer disease
Abstract:
Computed Tomographic (CT) imaging provides precise information about the
size, shape, and location of tumors. The aim of this study is to evaluate the CT
imaging patterns of lung cancer based on cell type. CT imaging features of 67 cases
with pathology were verified and collected between 1995-2000 and were
retrospectively analyzed for size, location, margins, internal characteristics and
metastasis. The number of squamous cell carcinoma, adenocarcinoma, large cell
carcinoma, and small cell carcinoma were 28, 23, 7, and 9 cases, respectively. The
accuracy, predictive value and 95% confidence interval (95%CI) were calculated.
There was a significant location of squamous cell carcinoma in central and
adenocarcinoma in the periphery (p<0.05). High incidence in squamous cell carcinoma
(29%) had cavitation. Central lesion with cavitation had possibility of squamous cell
carcinoma, at least for the differentiation of characteristics presented in CT imaging,
such as size, edge, infiltration, internal characteristics, lymph node enlargement,
pleural effusion, and metastasis to other organs. We can not evaluate cell type of lung
cancer from CT imaging patterns. The accuracy of CT imaging for evaluated
squamous cell carcinoma, adenocarcinoma, large cell carcinoma, and small cell
carcinoma were 82% (95%CI 73-91), 65% (95%CI 54-77), 0% and 44% (95%CI 33-
56), respectively. Predictive value were 64% (95%CI 52-75), 65% (95%CI 54-77),
0%, and 57% (95%CI 45-69), respectively. In conclusion, we can not evaluate
pathological cell type of primary lung cancer from CT imaging, because the accuracy
is low. However, CT imaging of the chest has usefulness to provide precise
information about the size, location, margin, internal characteristics and metastasis.