Korrakot Weratean. Effect of cereals and nata de coco supplementation in hyperlipidemia . Master's Degree(Nutrition). Mahidol University. : Mahidol University, 2004.
Effect of cereals and nata de coco supplementation in hyperlipidemia
Abstract:
The purpose of this study was to evaluate the effect of the cereals and nata de
coco supplementation on lipid status, serum vitamin A, β-carotene, vitamin E levels,
lipid peroxidation and its acceptability, tolerance, compliance and safety in twenty two
subjects with hyperlipidemia. Subjects consisted of eleven men and eleven women
aged 32-75 yr, and had serum TC level of > 5.2 mmol/L, serum TG level of > 1.69
mmol/L and LDL-C level of >3.4 mmol/dL. The study consisted of four wks of
control and twenty wks of supplementation period. They were supplemented twice
daily with 15g of the supplement for twenty wks. This 30g of supplement provided
122.6 kcal, 5.5g of protein, 0.5g of fat and 24.1g of carbohydrate and 2.76g of fiber.
After twenty wks, the subjects were classified into two groups, according to their
compliance, group A; compliance > 90 % of assigned supplement intake and group
B; compliance < 90 % of assigned supplement intake.
In group A significant differences were seen between the mean TG level at wk
zero and the mean values at wk four, eight, and twelve (p < 0.05) but no significant
differences were seen in TC, LDL-C and HDL-C expect TC level at wk sixteen was
significantly lower than that at wk zero (p <0.05). All subjects had normal serum
vitamin A, β-carotene and vitamin E levels during the study and had no significant
differences from wk zero. Serum MDA concentration of the twenty two subjects at wk
four, eight, twelve, sixteen and twenty were significantly decreased from those at wk
zero. (p<0.05)