Cholinesterase screening test among organophosphate exposure of rice farmers in Southern Vietnam

Name: Au Bich Thuy

LCSH: Rice farmers

MeSH: Cholinesterases

MeSH: Occupational Exposure

Abstract: A cross-sectional study was carried out among rice farmers in My Huong commune, Southern Vietnam to assess the effects of occupational exposure to organophosphates (OPs) on cholinesterase (ChE) enzyme activity. A questionnaire with a face-to-face interview was used to establish exposure patterns of 325 subjects based on the recommendation of the United States Center for Disease Control. Blood from the finger prick of each subject was collected after the interview to measure cholinesterase enzyme level by Reactive Paper. STATA software was used to analyze the correlation between occupational exposure and cholinesterase enzyme activity with µ equaled to 0.05. The results showed that 44% of the farmers had a Cholinesterase enzyme level as normal, 42.2% as safe and 13.8% as risk. There were many contributors to the Cholinesterase enzyme level: (1) age of the farmers: the older the farmers were, the less risk they had (2) amount of rice land possessed: the more land the farmers had the less risk they had; (3) frequency of using organophosphate pesticides on rice: the more often they use organophosphate pesticides, the greater risk they had; (4) washing the spray can after spraying: the one who washed the spray can was at a greater risk than those who did not. Personal protective equipment was almost completely ignored by the local farmers. The most common working clothes were ordinary clothes with a long sleeved shirt, long trousers and cloth hats. Any protective effect of these outfits was not detected. Clinical symptoms were not associated with ChE enzyme level in the study. These findings have suggested that there should be an intervention that make the farmers translate their knowledge into practice. Besides this, personal protective equipment that is suitable for the hot weather should be made available for use. Notably, the study found that snail epidemic had led the farmers to overuse mollusticides. Proper assessment on the impacts of this matter is necessary to deal with the problem.

Mahidol University

Address: NAKHON PATHOM

Email: liwww@mahidol.ac.th

Name: Voranuch Wangsuphachart

Role: Thesis Advisors

Created: 2003

Modified: 2553-01-26

Issued: 2009-11-30

วิทยานิพนธ์/Thesis

application/pdf

ISBN: 9740432832

CallNumber: TH A887c 2003

eng

Spatial: Vietnam

DegreeName: Master of Science

Level: Master's Degree

Descipline: Tropical Medicine

Grantor: Mahidol University

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