Saengduean songsri. Validity of dose distribution of electron beam therapy of ADAC pinnacle3 treatment planning system version 7.6C . Master's Degree(Medical Physics). Mahidol University. : Mahidol University, 2008.
Validity of dose distribution of electron beam therapy of ADAC pinnacle3 treatment planning system version 7.6C
Abstract:
The purpose of this study is to investigate the accuracy of the dose computation
of the implemented electron beam dose calculation algorithm in Pinnacle3 treatment
planning system version 7.6C (Philips radiation Oncology System, Milpitas, CA). The
investigation includes comparisons of measured relative dose distribution with
calculated dose distributions and also comparisons of measured and calculated relative
output factor. The testing process consisted of five experiments which were designed
to represent typical clinical applications for electron beam therapy. The experiments
consisted of standard fields, shaped fields, extended SSDs, oblique fields and internal
heterogeneities (air and bone) and were most often irradiated with 6, 9 and 12 MeV
electrons from the Varian Clinac 2100C linear accelerator. The accuracy of relative
doses in standard fields with perpendicular incidences at standard and extended SSD,
shaped fields and internal heterogeneities conditions was reasonably in agreement with
the results. However, for the inhomogeneity test, the deviation between measurements
and calculations at the interface area of an air cavity was up to 7%. The dose
calculation in the interface area of a bone cavity was closer to the measurement than
that in the border area of an air cavity and was within criteria of acceptability (<7%).
The agreement between calculations and measurements in the SSD correction factor
was smaller than 2%. For shaped fields and oblique beam incidence condition, the
deviations of the output factor were smaller than 5%. This study indicates that the
Pinnacle TPS is appropriated for electron dose calculations in the clinical radiation
therapy. However, the physicist and clinician should be aware of the limitations of the
dose calculation at the interface area of the internal heterogeneities