Abstract:
The purposes of this research were to examine the prevalence of anxiety and depression and related factor in breast cancer patients receiving chemotherapy at king chulalongkorn hospital. The research design was cross sectional descriptive study. The sample was 236 breast cancer patients who receiving chemotherapy at king chulalongkorn hospital. The instruments were general demographic data, Thai Hospital Anxiety and Depression Scales (Thai HADS), Life Stress Event Questionnaires and the instrument to measure Social Support. All data were analyzed with the SPSS / FW program to determine percentage, mean, standard deviation, Chi-square, One-way ANOVA, Pearsons Product Moment Correlation Coefficient and Stepwise Multiple Regression Analysis were used to determine factors to anxiety and depression. The major findings were as follows: The prevalence of anxiety and depression in breast cancer patients receiving chemotherapy were 8.9% and 9.3%. Factors associated to anxiety are as follows: Status: Subjects whose marital status had higher anxiety than those single (p<0.05). Age of diagnosis: Subjects whose old ages had higher anxiety than those younger (p<0.05). Severity of pain from breast cancer: Subjects whose high severity of pain had higher anxiety than those low severity of pain (p<0.05). Side effects before and after receiving chemotherapy: Subjects whose high side effects had higher anxiety than those low side effects (p<0.05, p<0.01). Life stress event: Subjects whose high number of life stress events had higher anxiety than those low number of life stress events (p<0.01). Factors associated to depression are as follows: Age: Subjects whose old ages had higher depression than those younger (p<0.05). Status: Subjects whose marital status had higher depression than those whose single (p<0.05). Age of diagnosis: Subjects whose old ages had higher depression than those younger (p<0.05). Severity of pain from breast cancer: Subjects whose high severity of pain had higher depression than those low severity of pain (p<0.05). Side effects before and after receiving chemotherapy: Subjects whose high side effects had higher depression than those low side effects (p<0.05, p<0.01). Life stress event: Subjects whose high number of life stress event had higher depression than those low number of life stress event (p<0.01). Social support: Subjects whose low social support had higher depression than those high social support (p<0.01). The factors which still predicted anxiety were insomnia symptom after receiving chemotherapy, severity of pain from breast cancer, life stress event, social support, fever and diarrhea symptom after receiving chemotherapy were predictive power as 23.9% (R2=0.239) of the variance. The factors which still predicted depression were fatigue symptom before receiving chemotherapy, social support, life stress event, age of diagnosis to breast cancer, age and anemia symptom after receiving chemotherapy werw predictive power as 27.9% (R2=0.279)