Experimental study of screen-printed lab-on-a-chip with conductive ink

Name: Thanakrit Thanacharoenchanaphas

Organization : King Mongkut's University of Technology North Bangkok. Department of Industrial Physics and Medical Instrumentation

Email : mosstnk1996@gmail.com

Name: Kessararat Ugsornrat

Organization : King Mongkut's University of Technology North Bangkok. Department of Industrial Physics and Medical Instrumentation

Email : kessararat.u@sci.kmutnb.ac.th

Name: Wichayaporn Kamsong

Organization : National Science and Technology Development Agency. Graphene and Printed Electronics for Dual-use Application Research Division

Email : wichayaporn.kam@ncr.nstda.or.th

Name: Triwit Phurksasukkasem

Organization : King Mongkut's University of Technology North Bangkok. Department of Industrial Physics and Medical Instrumentation

Email : triwit.phurk@hotmail.com

Name: Chanpen Karuwan

Organization : National Science and Technology Development Agency. Graphene and Printed Electronics for Dual-use Application Research Division

Email : chanpen.kar@nstda.or.th

Name: Adisorn Tuantranont

Organization : National Science and Technology Development Agency. Graphene and Printed Electronics for Dual-use Application Research Division

Email : adisorn.tua@nstda.or.th

keyword: Lab-on-a-chip devices

LCSH: Screen process printing

; Conductive inks

LCSH: Microfluidics

LCSH: Biochips

Abstract: In this work, a multifunctional lab-on-a-chip device was developed by integrating electrowetting-on-dielectric (EWOD) and electrochemical sensing on a single microfluidic platform. The device utilizes screen-printed electrodes fabricated with conductive ink on a flexible substrate. The microchannel design was modified from a traditional T-junction to an H-junction configuration, enabling the precise manipulation of up to four discrete droplets for complex reagent handling. The electrochemical sensing module utilizes a threeelectrode configuration, comprising a carbon working electrode, carbon counter electrode, and a silver/silver chloride (Ag/AgCl) reference electrode. Electrochemical action was evaluated using cyclic voltammetry (CV) in 0.1 M phosphate-buffered saline (PBS) at pH 7.0. NADH was used as the target analyte due to its relevance in enzymatic lactate detection pathways. A distinct oxidation peak for NADH was observed at approximately +0.6 V (vs. Ag/AgCl), confirming the system’s capability for NADH detection and its potential as a platform for indirect lactate sensing via electrochemical methods.

King Mongkut's University of Technology North Bangkok. Central Library

Address: BANGKOK

Email: library@kmutnb.ac.th

Created: 2025

Modified: 2026-01-07

Issued: 2026-01-07

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BibliograpyCitation : In IEEE Thailand Section. Antennas and Propagation/Electron Devices/Microwave Theory and Techniques Joint Chapter, Electrical Engineering/Electronics, Computer, Telecommunications, and Information Technology Association, and King Mongkut's University of Technology North Bangkok. The 5th Research, Invention and Innovation Congress (RI2C 2025) (pp.147-150). Bangkok : IEEE Thailand Section

eng

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