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Nichakorn Suk-in. Development of cellulose nanocrystals from waste cotton fabric and polyvinyl alcohol composite hydrogel as non-invasive colorimetric sensor for cysteine detection. Master's Degree(Materials Innovation and Technology). Thammasat University. Thammasat University Library. : Thammasat University, 2025.
Development of cellulose nanocrystals from waste cotton fabric and polyvinyl alcohol composite hydrogel as non-invasive colorimetric sensor for cysteine detection
การพัฒนาวัสดุเชิงประกอบไฮโดรเจลเซลลูโลสนาโนคริสตัลจากขยะผ้าฝ้ายและโพลิไวนิลแอลกอฮอล์เพื่อประยุกต์ใช้งานเป็นตัวรับรู้เชิงสีแบบไม่รุกรานสำหรับการตรวจวิเคราะห์ซิสเตอีน
Name: Nichakorn Suk-in
keyword:
Cotton fabric waste
;
Hydrogel
Abstract:
Cellulose nanocrystals (CNCs) extracted and purified from cotton fabric waste serve as a promising reinforcing material for developing hydrogel-based colorimetric sensors. The synthesized CNCs were analyzed using X-ray diffraction spectroscopy (XRD), and Transmission electron microscopy (TEM). Then, the PV/Cu²⁺-CNCs/CNFs/PVA hydrogel was synthesized via chemical crosslinking using borax. With the integration of CNCs, the sensor's sensitivity was notably improved, allowing for a more distinct color change visible to the naked eye. Furthermore, the as-prepared hydrogel was applied as a non-invasive urinary cysteine colorimetric sensor using an indicator-displacement assay (IDA). This sensor exhibits a visible color transition from greenish-blue to orange-red in the presence of cysteine, with a linear range of 0-0.6 g/L and a limit of detection (LOD) of 0.017 g/L, covering cut-off (0.25 g/L) in human urine for monitoring Alzheimers disease. Ultimately, this hydrogel-based cysteine sensor was successfully tested in artificial urine samples with acceptable results. Consequently, this platform has a potential for Alzheimers disease monitoring in the near future.
Thammasat University. Thammasat University Library
Address:
BANGKOK
Email:
preserv@tu.ac.th
Name: Sarute Ummartyotin
Role:
advisor
Name: Nadnudda Rodthongkum
Role:
co-advisor
Created:
2025
Modified:
2025-11-19
Issued:
2025-11-19
วิทยานิพนธ์/Thesis
application/pdf
eng
DegreeName: Master of Science
Level: Master's Degree
Descipline: Materials Innovation and Technology
Grantor: Thammasat University
©copyrights Thammasat University
RightsAccess:
ใช้เวลา
0.039028 วินาที
Nichakorn Suk-in
| Title | Contributor | Type |
|---|---|---|
| Development of cellulose nanocrystals from waste cotton fabric and polyvinyl alcohol composite hydrogel as non-invasive colorimetric sensor for cysteine detection
มหาวิทยาลัยธรรมศาสตร์ Nichakorn Suk-in | Sarute Ummartyotin Nadnudda Rodthongkum | วิทยานิพนธ์/Thesis |
Sarute Ummartyotin
Nadnudda Rodthongkum