Prevalence of Psychiatric Symptoms Associated with Vitamin D Level in Long COVID: Preliminary Study

Name: Karn Matangkha

Address: 333 Moo1, Thasud, Muang, Chiang Rai 57100

Organization : School of Medicine, Mae Fah Luang University

Email : library@mfu.ac.th

Name: Jarasphol Rintra

Name: Vichit Punyahotara

Name: Phakkharawat Sittiprapaporn

keyword: Long COVID

ThaSH: Medicine

; COVID-19

ThaSH: Post COVID-19 condition (Disease)

; Psychiatric Symptoms

ThaSH: COVID-19 (Disease)

; Vitamin D

ThaSH: Psychiatry

Abstract: Background: Long COVID is a condition where individuals continue to experience persistent symptoms after recovering from the initial COVID-19 infection. Vitamin D is one of the vital minerals for maintaining normal health conditions and may be associated with the psychiatric symptoms of long COVID. Objective: To examine the prevalence of psychiatric symptoms in long COVID-19 patients in association with vitamin D levels. Materials and Methods: This study employed a cross-sectional descriptive design, focusing on 170 patients who had previously contracted the COVID-19 virus at Foresta Clinic. The data collected included demographic data, vitamin D levels, and psychiatric symptoms in long COVID (anxiety, depression, and sleep disorders). Result: The study results indicated a female-to-male ratio of 1.1:1 among the patients, with a mean age of 45.87 ± 8.65 years. Additionally, 62.4% had received three doses of the COVID-19 vaccine. The median blood vitamin D level was 22.96 ng/mL (IQR 18.77, 31.7), with 41.2% of participants showing insufficiency, 30.6% showing deficiency, and 28.2% having sufficient levels. Overall, psychiatric symptoms were found in 30.0% of the patients, with anxiety occurring in 15.3%, depression in 7.1%, and sleep disorders in 21.2%. Participants with psychiatric symptoms had significantly lower blood vitamin D levels compared to those without symptoms (p < 0.05). The prevalence of psychiatric symptoms was highest among those with vitamin D deficiency (46.2%), followed by those with vitamin D insufficiency (25.7%), and it was lowest in the vitamin D sufficient group (18.8%). Conclusion: Maintaining and assessing vitamin D levels in long-term COVID patients may help prevent or reduce the severity of psychiatric symptoms. Further research is needed to evaluate the effectiveness of vitamin D supplementation in long COVID patients with low vitamin D levels, as well as to monitor and assess psychological tests continuously.

Mae Fah Luang University. Learning Resources and Educational Media Centre

Address: CHIANG RAI

Email: library@mfu.ac.th

Modified: 2025-07-25

Issued: 2025-07-25

บทความ/Article

application/pdf

BibliograpyCitation : GMS Medicine Journal. Vol.5, No.3 (September - December 2025) : p.149-158

GMS Medicine Journal. Vol.5, No.3 (September - December 2025) : p.149-158

eng

©copyrights Mae Fah Luang University

ลำดับที่.	ชื่อแฟ้มข้อมูล	ขนาดแฟ้มข้อมูล	จำนวนเข้าถึง	วัน-เวลาเข้าถึงล่าสุด
1	2025-v05-no3-p.149-158.pdf	265.98 KB

ใช้เวลา

-0.981823 วินาที