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Witawat Jangiam. Synthesis, swelling behavior, and niacinamide release of 1,4-butanediol diglycidyl ether-crosslinked levan hydrogels from Bacillus siamensis. (). . : , 2025.
Synthesis, swelling behavior, and niacinamide release of 1,4-butanediol diglycidyl ether-crosslinked levan hydrogels from Bacillus siamensis
Name: Pongtorn Phengnoi
Organization :
Burapha University. Faculty of Engineering
Name: Cherdphong Seedao
Organization :
Burapha University. Faculty of Engineering
Name: Suphak Nakthongkham
Organization :
Burapha University. Faculty of Engineering
Name: Pitchayanin Intarawichai
Organization :
Burapha University. Faculty of Engineering
Name: Phumipat Saelao
Organization :
Burapha University. Faculty of Engineering
Name: Witawat Jangiam
Organization :
Burapha University. Faculty of Engineering
Email :
witawat@eng.buu.ac.th
keyword:
Niacinamide
Abstract:
Levan is a fructan polysaccharide used in a broad range of applications, including
cosmetics, pharmaceuticals, and medicine. This study focused on the synthesis of
hydrogel based on levan produced from Bacillus siamensis crosslinked with 1,4-
butanediol diglycidyl ether (BDDE) to control niacinamide release. The swelling level
of levan hydrogel was observed at different levan concentrations (5, 7, and 10%w/v), pH
values (5.5, 7.4, and 9.0), and temperatures (25, 32, 37, and 50 °C). The results showed
that levan concentrations affected both the strength of the hydrogel structure and the
swelling level, with 10% w/v levan exhibiting the highest swelling level of 2.64. Levan
hydrogel (10% w/v levan) demonstrated a higher swelling level in Tris-HCl buffer (pH
9.0) compared to phosphate-buffered saline (pH 7.4) and acetate buffer (pH 5.5).
However, temperatures ranging from 25 to 50 °C had a minor effect on the swelling level
of the levan hydrogel. In a 10%w/v levan hydrogel, niacinamide entrapment reached
31.27%, and release reached 93.83% within 35 minutes. These results indicate levan has
potential in drug delivery applications
Address:
BANGKOK
Email:
library@kmutnb.ac.th
Created:
2025
Modified:
2025-07-21
Issued:
2568-07-21
บทความ/Article
application/pdf
BibliograpyCitation :
In Thai Institute of Chemical Engineering and Applied Chemistry and Khon Kaen University. Faculty of Engineering. The 34th Thai Institute of Chemical Engineering and Applied Chemistry International Conference (TIChE 2025) (TIChE 2025 TIChE-AM-04). Bangkok : Thai Institute of Chemical Engineering And Applied Chemistry, 2025
eng
©copyrights King Mongkut's University of Technology North Bangkok
RightsAccess:
ใช้เวลา
0.037001 วินาที
Pongtorn Phengnoi
| Title | Contributor | Type |
|---|---|---|
| Synthesis, swelling behavior, and niacinamide release of 1,4-butanediol diglycidyl ether-crosslinked levan hydrogels from Bacillus siamensis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Pongtorn Phengnoi;Cherdphong Seedao;Suphak Nakthongkham;Pitchayanin Intarawichai;Phumipat Saelao;Witawat Jangiam | บทความ/Article |
Cherdphong Seedao
| Title | Contributor | Type |
|---|---|---|
| Synthesis, swelling behavior, and niacinamide release of 1,4-butanediol diglycidyl ether-crosslinked levan hydrogels from Bacillus siamensis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Pongtorn Phengnoi;Cherdphong Seedao;Suphak Nakthongkham;Pitchayanin Intarawichai;Phumipat Saelao;Witawat Jangiam | บทความ/Article | |
| Influence of CaO on the durability of geopolymer in acidic environments
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Cherdphong Seedao;Valix, Marjorie | บทความ/Article |
Suphak Nakthongkham
| Title | Contributor | Type |
|---|---|---|
| Synthesis, swelling behavior, and niacinamide release of 1,4-butanediol diglycidyl ether-crosslinked levan hydrogels from Bacillus siamensis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Pongtorn Phengnoi;Cherdphong Seedao;Suphak Nakthongkham;Pitchayanin Intarawichai;Phumipat Saelao;Witawat Jangiam | บทความ/Article |
Pitchayanin Intarawichai
| Title | Contributor | Type |
|---|---|---|
| Synthesis, swelling behavior, and niacinamide release of 1,4-butanediol diglycidyl ether-crosslinked levan hydrogels from Bacillus siamensis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Pongtorn Phengnoi;Cherdphong Seedao;Suphak Nakthongkham;Pitchayanin Intarawichai;Phumipat Saelao;Witawat Jangiam | บทความ/Article |
Phumipat Saelao
| Title | Contributor | Type |
|---|---|---|
| Synthesis, swelling behavior, and niacinamide release of 1,4-butanediol diglycidyl ether-crosslinked levan hydrogels from Bacillus siamensis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Pongtorn Phengnoi;Cherdphong Seedao;Suphak Nakthongkham;Pitchayanin Intarawichai;Phumipat Saelao;Witawat Jangiam | บทความ/Article |
Witawat Jangiam
| Title | Contributor | Type |
|---|---|---|
| Synthesis, swelling behavior, and niacinamide release of 1,4-butanediol diglycidyl ether-crosslinked levan hydrogels from Bacillus siamensis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Pongtorn Phengnoi;Cherdphong Seedao;Suphak Nakthongkham;Pitchayanin Intarawichai;Phumipat Saelao;Witawat Jangiam | บทความ/Article |