Effect of open elliptical reflector shape on pressure gradient during shock wave focusing

Name: Taniguchi, Masaya

Organization : Nara College. National Institute of Technology

Name: Nitta, Tetsuro

Organization : Nara College. National Institute of Technology

Name: Fukuoka, Hiroshi

Organization : Nara College. National Institute of Technology

Email : fukuoka@mech.nara-k.ac.jp

Name: Suda, Atsushi

Organization : Nara College. National Institute of Technology

Name: Hiro, Kazuki

Organization : Nara College. National Institute of Technology

Name: Nakagawa, Keiichi

Organization : University of Tokyo

keyword: Underwater shock wave

; Focusing shock wave

; Open elliptical reflector

; Numerical calculation

; Optical waveguide

Abstract: Optogenetics is a technology to study brain cell function by irradiating light directly onto specific brain cells and partially controlling neurons' activity. However, the ability to deliver light into deep brain structures is limited due to absorption in the surrounding tissue. To solve this problem, we propose a novel approach to use focused underwater shock waves as pseudo-optical fibers. Underwater shock waves are focused by open elliptical reflectors, which have one of their focal points open. The elliptical reflector must be cut to place the focal point inside the brain. In this study, we investigated the relationship between the pressure gradient generated by the focusing of the underwater shock waves and the shape of the open elliptical reflectors. As its numerical experimental tool, ANSYS AUTODYN, was used to calculate the pressure gradient for different shapes of open elliptical reflectors. The parameters used in the calculations were the flatness of the reflector and the open ratio of the reflector. We found that for open elliptical vessels with the open ratio of 0.2, 0.3, 0.4, 0.5, and 0.6, decreasing the flatness from 0.5 to 0.1 increased the pressure gradient by a maximum of 15.2 MPa/mm. Similarly, decreasing the open ratio from 0.6 to 0.2 increased the pressure gradient by a maximum of 12.5 MPa/mm. Our results provide a basis for the design of open elliptical reflectors for use in optogenetics

King Mongkut's University of Technology North Bangkok. Central Library

Address: BANGKOK

Email: library@kmutnb.ac.th

Created: 2024

Modified: 2024-12-18

Issued: 2024-12-18

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BibliograpyCitation : In Thai Society of Mechanical Engineers (TSME) and Chiang Mai University. The 13th TSME International Conference on Mechanical Engineering (TSME-ICoME 2023) (pp.785-791). Chiang Mai : Chiang Mai University, 2023

eng

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