Extraction, preliminary phytochemical screening and antioxidant properties of ethanolic crude extract of Madan (Garcinia schomburgkiana Pierre)

Name: Supranee Pimpila

Organization : Rajamangala University of Technology Krungthep. Faculty of Science and Technology

Name: Worawat Chanmin

Organization : Rajamangala University of Technology Krungthep. Faculty of Science and Technology

Name: Irawan Cheunangul

Organization : Rajamangala University of Technology Krungthep. Faculty of Science and Technology

Name: Winai Oungpipat

Organization : Rajamangala University of Technology Krungthep. Faculty of Science and Technology

Email : winai.o@mail.rmutk.ac.th

keyword: Garcinia schomburgkiana

LCSH: Madan -- Therapeutics use

Abstract: Madan (Garcinia schomburgkiana Pierre) is an edible perennial fruit belonging to the Guttiferae family. Local people consumed it fresh and fermented.Madan leaves, root and fruit are also traditionally used as an expectorant, improvement of menstrual blood quality, treatment of coughs, treatment of diabetes and as a laxative. The aim of the present study was to explore the phytochemical constituents, to evaluate the total phenolic and total flavonoid contents and antioxidant activity of the crude fruits and leaves of G. schomburgkiana Pierre extracts. The extraction process was performed using 50 g each of the dried powder of G. schomburgkiana fruits and leaves soaked in 250 ml of ethanol and macerated for 7 days at room temperature. The crude extract yields obtained were 23.13±3.17 g and 6.46±2.64 g for fruit and leaf extracts, respectively. The phytochemical screening of the Madan fruit extracts revealed the presence of flavonoids, tannins and saponins, while the Madan leaf extracts were found to contain flavonoid, steroids, tannins, glycosides, sterols, and saponins. The total phenolic contents in Madan fruit and leaf extracts using Folin– Ciocalteu method were estimated to be 22.0±1.47 and 10±5.28 mg gallic acid equivalent per 1 g of extract, respectively. Total flavonoid contents of Madan fruit and leaf extracts using aluminum chloride colorimetric method were found to be 0.4083±0.034 and 92.1486±0.614 mg quercetin equivalent per 1 g of extract, respectively. The antioxidant activity of fruit and leaf extracts and standard gallic acid using 2,2-diphenyl-1- picrylhydrazyl (DPPH) assay showed the IC50 values of 1694.42±39.50, 275.55±2.78 and 140.68±14.70 mg/ml, respectively.

King Mongkut's University of Technology North Bangkok. Central Library

Address: BANGKOK

Email: library@kmutnb.ac.th

Created: 2024

Modified: 2024-12-04

Issued: 2024-12-04

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BibliograpyCitation : In Kasetsart University. Faculty of Science. The Pure and Applied Chemistry International Conference 2024 (PACCON 2024) (pp.847-853). Bangkok : Kasetsart University, 2024

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