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Supason Wanichwecharungruang. Water dispersible α-mangostin by self-assembly process. (). King Mongkut's University of Technology North Bangkok. Central Library. : , 2020.
Water dispersible α-mangostin by self-assembly process
Name: Jutamad Bumrung
Organization :
Chulalongkorn University. Faculty of Science
Name: Chanpen Chanchao
Organization :
Chulalongkorn University. Faculty of Science
Name: Tanapat Palaga
Organization :
Chulalongkorn University. Faculty of Science
Organization :
Chulalongkorn University. Faculty of Science
Email :
psupason@chula.ac.th
keyword:
Alpha-mangostin
ThaSH:
Plant extracts
ThaSH:
Xanthone
ThaSH:
Nanoparticles
Abstract:
α-Mangostin, a major bioactive compound in Garcinia mangostana Linn, displays various interesting biological activities. However, the poor water solubility of α-mangostin has limited its use in the cosmetics and pharmaceutics. Here, we solve α-mangostin's solubility by creating water dispersible α-mangostin particles through self-assembly process without any auxiliary agents such as polymers or surfactants. Our self-assembly process gives 100 percent pure α-mangostin spherical particles with nanometer sizes. The solid state 1H NMR, FT-IR, X-ray diffraction pattern and Thermogram of the particles indicate that molecular arrangement, intermolecular H-bonding interactions and molecular packing of the α-mangostin molecules in the particles are different from those observed in the original α-mangostin solid. The water dispersible α-mangostin particles show a similar anti-acne activity to that of the original α-mangostin. The anti-inflammatory activity of α-mangostin nanoparticles is 5 times higher than that of the original α-mangostin at the concentration of 12.7 ppm, which is the concentration that is not toxic to RAW 264.7 cell line.
King Mongkut's University of Technology North Bangkok. Central Library
Address:
BANGKOK
Email:
library@kmutnb.ac.th
Created:
2020
Modified:
2024-10-16
Issued:
2024-10-16
บทความ/Article
application/pdf
BibliograpyCitation :
In the Chemical Society of Thailand under the Patronage of Professor Dr. HRH Princess Chulabhorn in association, Thammasat University Faculty of Science and Technology. The Pure and Applied Chemistry International Conference 2020 (PACCON 2020) (MN157-162). Bangkok : Thammasat University
eng
©copyrights King Mongkut's University of Technology North Bangkok
RightsAccess:
ใช้เวลา
0.02303 วินาที
Jutamad Bumrung
| Title | Contributor | Type |
|---|---|---|
| Water dispersible α-mangostin by self-assembly process
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Jutamad Bumrung;Chanpen Chanchao;Tanapat Palaga;Supason Wanichwecharungruang | บทความ/Article |
Chanpen Chanchao
| Title | Contributor | Type |
|---|---|---|
| Water dispersible α-mangostin by self-assembly process
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Jutamad Bumrung;Chanpen Chanchao;Tanapat Palaga;Supason Wanichwecharungruang | บทความ/Article |
Tanapat Palaga
| Title | Contributor | Type |
|---|---|---|
| Screening for mycobacterium tuberculosis antigenic peptide for diagnostic kit for elephant tuberculosis by interferon gamma release assay (IGRA)
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Chitsuda Pongma;Songkiat Songthammanuphap;Therdsak Prammananan;Saradee Warit;Wanlaya Tipkantha;Erngsiri Kaewkhunjob;Wandee Yindeeyoungyeon;Tanapat Palaga | บทความ/Article | |
| Water dispersible α-mangostin by self-assembly process
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Jutamad Bumrung;Chanpen Chanchao;Tanapat Palaga;Supason Wanichwecharungruang | บทความ/Article |
Supason Wanichwecharungruang
| Title | Contributor | Type |
|---|---|---|
| Water dispersible α-mangostin by self-assembly process
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Jutamad Bumrung;Chanpen Chanchao;Tanapat Palaga;Supason Wanichwecharungruang | บทความ/Article |