Physical and Chemical properties of Medical Lubricant Made from Rice Starch

Name: Sittiporn Punyanitya

Address: 333 Moo1, Thasud, Muang, Chiang Rai 57100

Organization : School of Medicine, Mae Fah Luang University

Email : library@mfu.ac.th

Name: Rungsarit Koonawoot

Name: Anucha Raksanti

Name: Phanlob Chankachang

keyword: Rice starch

ThaSH: Medicine

; Medical lubricant

ThaSH: Rice flour

; Gelatinized

ThaSH: Lubrication and lubricants

; Water soluble

ThaSH: Viscosity

; Viscosity

Abstract: Background: Gel lubricants belong to pharmaceuticals that are included in the cost of diagnostics. This material is pharmaceutical product in gel form that has been synthesized for medical or veterinary use. It is a lubricant for various body parts for surgery, physical examination, or as a reduced friction agent between the body and medical equipment. Normally, this product must be imported from foreign contries billions baht per year. Objective: This research aims to produce medical lubricant gel from rice starch, a Thai agricultural raw material that helps reduce the problem of importation from abroad. Materials and Method: The main raw material is pure rice starch, pharmaceutical grade added in different amounts of 37%, 54%, 63%, 70%, and 80% by weight mixed with additives. These additives are sodium hydroxide, carboxyl-methyl cellulose, sucrose, glycerin, and methylparaben. The method of combining the solution with the solution determines the physicochemical characteristics of commercial lubricant gel, compared with the gel samples of this research by using the SEM-EDS technique, pH analysis, and the FTIR technique. Results: The results showed that the acidity and alkalinity of the two commercial gels compared to the sample gel. The pH is in the range between can be used according to ISO 13485: 2003 in the same range, pH 6-7. The morphology of the commercial gel found that the lubricant gel from the rice starch was uniformly distributed in the structure of the gel. The viscosity of the commercial lubricant gel is 2,991 ± 60.92 cP. This value is near the viscosity of gel 80 wt% of rice starch was 2,936 ± 18.52 cP. The chemical composition of the commercial gels consists of the carbon and oxygen function groups. However, the FTIR technique found amounts of synthetic substances such as sulfur, chloride, nitrogen, and zinc, which may irritate to skin. Meanwhile, the rice gel of this research found that there are carbon compounds, oxygen, and sodium, which are more than 95% organic compounds, and therefore 100% safe. Conclusion: The study of lubricating gel made from rice starch by finding the physical, chemical, and biological properties. This project found that rice lubricant gel contains 80% of rice starch by weight. It is the best ingredient which has the same safety and lubrication performance as a commercial gel. Therefore, lubricant gel from rice starch can replace the gel ordered from abroad.

Mae Fah Luang University. Learning Resources and Educational Media Centre

Address: CHIANG RAI

Email: library@mfu.ac.th

Modified: 2024-10-07

Issued: 2024-10-07

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GMS Medicine Journal Vol. 4 No. 3 September-December 2024 • 125-131

eng

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