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Ammarin Thakkinstian. Comparison of regular, as-needed, and combined use of inhaled corticosteroids and other asthma treatments for mild asthma in children and adolescents/adults: a systematic review and meta-analysis. (). King Mongkut's University of Technology North Bangkok. Central Library. : , 2023.
Comparison of regular, as-needed, and combined use of inhaled corticosteroids and other asthma treatments for mild asthma in children and adolescents/adults: a systematic review and meta-analysis
Name: Prapaporn Pornsuriyasak
Organization :
Mahidol University. Ramathibodi Hospital
Email :
prapaporn.por@mahidol.edu
Name: Sunatee Sa-nguansai
Organization :
Mahidol University. Ramathibodi Hospital
Name: Kunlawat Thadanipon
Organization :
Mahidol University. Ramathibodi Hospital
Name: Suparee Boonmanunt
Organization :
Mahidol University. Ramathibodi Hospital
Name: Ammarin Thakkinstian
Organization :
Mahidol University. Ramathibodi Hospital
keyword:
Leukotriene Antagonists
LCSH:
Antiasthmatic agents
LCSH:
Meta-analysis
Abstract:
Regular use of inhaled corticosteroids (ICS) is recommended in mild asthma. Efficacy of this approach in comparison with as-needed ICS with/without formoterol, long-acting beta-2 agonists (LABA), short-acting beta-2 agonists (SABA), leukotriene antagonists (LTRAs), or tiotropium is unclear. We aimed to compare the efficacy between regular ICS and other treatments in children (age > 6) and adolescents/adults with mild asthma. A systematic review and meta-analysis of all randomized controlled trials (RCTs) was conducted. PubMed, Scopus, and ClinicalTrials.gov were searched up to August 2022. The outcomes of interest were number of exacerbations and symptom scores, for which the risk ratios (RR) and standardized mean differences (SMD) were estimated. Thirteen RCTs in children and 29 in adolescents/adults were included. The results revealed that in children (asthma step 2, 5 studies), regular ICS was similar to as-needed ICS in reducing exacerbations (RR [95% confidence interval]: 0.83 [0.63-1.25]), but better than LTRAs (RR: 0.82 [0.69-0.96]) and as-needed SABA (RR: 0.63 [0.49-0.82]). In adolescents/adults (asthma step 2, 12 studies), regular ICS reduced severe exacerbations compared to as-needed SABA (RR: 0.61 [0.46-0.80]), but inferior to as-needed ICS/formoterol (RR: 1.36 [1.03-1.80] and combination of ICS/LABA (RR: 1.54 [1.19-2.00]). In adults (N=7), symptom scores were better improved with regular ICS than as-needed SABA (SMD: -0.44 [-0.68 to -0.21]). In conclusion, to prevent exacerbation, regular and as-needed use of ICS are not different, and they are better than LTRAs and as-needed SABA in pediatric mild asthma, while as-needed ICS/formoterol and regular ICS/LABA are better than ICS-alone in adolescents/adults.
King Mongkut's University of Technology North Bangkok. Central Library
Address:
BANGKOK
Email:
library@kmutnb.ac.th
Created:
2023
Modified:
2024-04-29
Issued:
2024-04-29
บทความ/Article
application/pdf
BibliograpyCitation :
In Rangsit University. The 8th RSU International Research Conference on Sciences and Technology 2023 (RSUCON 2023) (pp.95-107). Pathum Thani : Rangsit University
eng
©copyrights King Mongkut's University of Technology North Bangkok
RightsAccess:
ใช้เวลา
0.036233 วินาที
Prapaporn Pornsuriyasak
| Title | Contributor | Type |
|---|---|---|
| Efficacy of EGFR-TKIS targeted therapy as adjuvant systemic treatment for non-small cell lung cancer: a systematic review and meta-analysis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Sunatee Sa-nguansai;Prapaporn Pornsuriyasak;Sasivimol Rattanasiri;Pawin Numthavaj;Ammarin Thakkinstian | บทความ/Article | |
| Comparison of regular, as-needed, and combined use of inhaled corticosteroids and other asthma treatments for mild asthma in children and adolescents/adults: a systematic review and meta-analysis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Prapaporn Pornsuriyasak;Sunatee Sa-nguansai;Kunlawat Thadanipon;Suparee Boonmanunt;Ammarin Thakkinstian | บทความ/Article |
Sunatee Sa-nguansai
| Title | Contributor | Type |
|---|---|---|
| Efficacy of EGFR-TKIS targeted therapy as adjuvant systemic treatment for non-small cell lung cancer: a systematic review and meta-analysis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Sunatee Sa-nguansai;Prapaporn Pornsuriyasak;Sasivimol Rattanasiri;Pawin Numthavaj;Ammarin Thakkinstian | บทความ/Article | |
| Comparison of regular, as-needed, and combined use of inhaled corticosteroids and other asthma treatments for mild asthma in children and adolescents/adults: a systematic review and meta-analysis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Prapaporn Pornsuriyasak;Sunatee Sa-nguansai;Kunlawat Thadanipon;Suparee Boonmanunt;Ammarin Thakkinstian | บทความ/Article |
Kunlawat Thadanipon
| Title | Contributor | Type |
|---|---|---|
| Comparison of regular, as-needed, and combined use of inhaled corticosteroids and other asthma treatments for mild asthma in children and adolescents/adults: a systematic review and meta-analysis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Prapaporn Pornsuriyasak;Sunatee Sa-nguansai;Kunlawat Thadanipon;Suparee Boonmanunt;Ammarin Thakkinstian | บทความ/Article | |
| Effects of repetitive peripheral magnetic stimulation on upper extremity function after stroke : a systematic review and meta-analysis
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Suparee Boonmanunt
| Title | Contributor | Type |
|---|---|---|
| Comparison of regular, as-needed, and combined use of inhaled corticosteroids and other asthma treatments for mild asthma in children and adolescents/adults: a systematic review and meta-analysis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Prapaporn Pornsuriyasak;Sunatee Sa-nguansai;Kunlawat Thadanipon;Suparee Boonmanunt;Ammarin Thakkinstian | บทความ/Article | |
| Effects of repetitive peripheral magnetic stimulation on upper extremity function after stroke : a systematic review and meta-analysis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Apisara Keesukphan;Monchai Suntipap;Kunlawat Thadanipon;Suparee Boonmanunt;Ammarin Thakkinstian | บทความ/Article |
Ammarin Thakkinstian
| Title | Contributor | Type |
|---|---|---|
| Detection of drug-associated Rhabdomyolysis through data mining techniques
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| Efficacy of EGFR-TKIS targeted therapy as adjuvant systemic treatment for non-small cell lung cancer: a systematic review and meta-analysis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Sunatee Sa-nguansai;Prapaporn Pornsuriyasak;Sasivimol Rattanasiri;Pawin Numthavaj;Ammarin Thakkinstian | บทความ/Article | |
| Comparison of regular, as-needed, and combined use of inhaled corticosteroids and other asthma treatments for mild asthma in children and adolescents/adults: a systematic review and meta-analysis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Prapaporn Pornsuriyasak;Sunatee Sa-nguansai;Kunlawat Thadanipon;Suparee Boonmanunt;Ammarin Thakkinstian | บทความ/Article | |
| Effects of repetitive peripheral magnetic stimulation on upper extremity function after stroke : a systematic review and meta-analysis
มหาวิทยาลัยเทคโนโลยีพระจอมเกล้าพระนครเหนือ Apisara Keesukphan;Monchai Suntipap;Kunlawat Thadanipon;Suparee Boonmanunt;Ammarin Thakkinstian | บทความ/Article | |
| Prediction of biological age from longitudinal data using mixed - effects linear regression and long short-term memory
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