Prevalence and factors associated with hepatitis B virus infection among blood donors at banadir hospital, Mogadishu, Somalia

Name: Abdirahman Khalif Mohamud

keyword: HBV

MeSH: Infection

Classification :.DDC: e-Theses

; Blood Donation

MeSH: Hepatitis B virus -- 306039

MeSH: Blood doners -- 306040

LCSH: Infection

LCSH: Hepatitis B virus -- 306039

LCSH: Blood doners -- 306040

Abstract: Background: Hepatitis B virus (HBV) infection is one of the leading causes of hepatocellular carcinoma (HCC) and liver cirrhosis. In Somalia, HBV prevalence and predictors among blood donors were not reported in the last three decades since the latest study reported 19% HBV prevalence in 1995 without investigating any risk factors and not only targeted blood donors. Hence, clinics showed a high burden of HBV. So that up-to-date information regarding the prevalence of HBV infection and associated risk factors among blood donors in Somalia is highly required and is vital for better treatment, and interventions, and might support national and international HBV strategies and eradication programs and policy makers as well. Therefore, the study aims to estimate the prevalence of hepatitis B virus infection and determine factors associated with it among blood donors at Banadir hospital, Mogadishu, Somalia. Method: A hospital-based cross-sectional study was implemented in blood donors who attended the blood bank of the study hospital between February to April 2023 after excluding those who did not verbally communicate, not hear, not mentally fit, not willing to participate, did not provide a blood sample, and those received a dose of the HB vaccine in the least 30 days to avoid transiently HBV positive. A 5-ml blood sample and a validated reliable questionnaire were used as a research tool. A rapid, qualitative, immunoassay called advanced quality one-step multi-HBV test was used to determine the presence or absence of HBV markers and markers were interpreted based on the CDC’s standardized HB serological interpretation guideline. Descriptive statistics are used for all characteristics. Logistic regression in univariate and multivariate models was used to determine the association between independent variables and outcome at a significant level of alpha=0.05 in the final model. Finding: A total of 494 blood donors participated in this study, almost all (93.9%) were male with a mean age of 31.58 (SD=8.116), over half (57.1%) were single and 30.5% were illiterate. The overall prevalence of hepatitis B virus (HBV) infection among blood donors was 9.7%; 9.3% were positive for HBsAg, 10.7% were positive for anti-HBs, and 9.7% were positive for anti-HBc. In Multivariable logistic regression, six (6) variables were found to be significantly associated with HBV infection; income of <200 USD$ (AOR=5.20, 95% CI=1.612-16.799), income between 200 to 400USD$ (AOR=3.59, 95% CI;1.385-9.345), joblessness (AOR=3.7695% CI=1.172-12.202), having a business occupation (AOR=3.35, 95% CI=1.241-9.086), having a history of STD (AOR=4.838, 95%CI=2.035-11.500), having a history of tooth extraction (AOR=6.90, 95% CI=2.668-17.881), share sharp equipment (AOR=2.90, 95%CI=1.075-7.825), and not have a history of HB vaccine (AOR=13.81, 95% CI=2.466-77.413). Conclusion: Blood donors in Mogadishu, Somalia suffers from a high burden of HBV infections. The implementation to reduce HBV infection must focus on low-income and jobless donors and those who have a history of STD, tooth extraction, sharing sharp equipment, and non-vaccinated donors.

Mae Fah Luang University. Learning Resources and Educational Media Center

Address: CHIANG RAI

Email: library@mfu.ac.th

Name: Pamornsri Inchon

Role: Advisor

Created: 2023

Modified: 2023-08-25

Issued: 2023-08-25

วิทยานิพนธ์/Thesis

application/pdf

CallNumber: e-Theses

eng

Spatial: Somalia 306038

DegreeName: Master of Public Health

Level: Master's Degree

Descipline: Border Health Management

Grantor: Mae Fah Luang University

©copyrights Mae Fah Luang University

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