Electrospun nanofibers containing ascorbic acid-loaded halloysite nanotubes for cosmetic applications

Name: Tachini Kaosamang

Organization : Kasetsart University. Faculty of Science

Email : fscikij@ku.ac.th

Name: Tachini Kaosamang

Organization : Kasetsart University. Faculty of Science

Email : orfsciwls@ku.ac.th

LCSH: Electrospinning

LCSH: Nanofibers

LCSH: Drug delivery systems

LCSH: Ascorbic acid

Abstract: The aims of this work are to synthesize ascorbic acid (AA) loaded-halloysite nanotubes (HNTs) and to incorporate HNTs/AA materials into the nanofiber mats fabricated from Sacran and polyvinyl alcohol PVA). Sacran is an ultrahigh-molecular weight natural polysaccharide and has recently been applied as an ingredient of cosmetic products due to its excellent viscoelasticity and high water-retention capability. AA was loaded into HNT nanotubes through cyclic vacuum pumping in/out process. The presence of AA in HNTs/AA was confirmed using Fourier transform-infrared spectroscopy. The nanofiber mats of PVA/Sacran containing HNTs/AA were fabricated using electrospinning technique. Surface morphology of the fabricated nanofiber mats was characterized using scanning electron microscopy (SEM). SEM images showed that the nanofibers were continuous, and HNTs/AA particles were uniformly distributed over the nanofiber mats. The verage diameter of the PVA/Sacran-HNTs/AA nanofibers was about 221 - 59 nm. Thermogravimetric analysis results revealed that incorporation of HNTs into the nanofibers resulted in an enhancement of their thermal stability. The in-vitro AA release profile of the nanofiber mats was examined using UV-Vis pectroscopy. This study demonstrates that the PVA/Sacran electrospun nanofibers containing HNTs/AA have promising potential as a material for use in cosmetics and personal-care products

King Mongkut's University of Technology North Bangkok. Central Library

Address: BANGKOK

Email: library@kmutnb.ac.th

Created: 2023

Modified: 2023-06-22

Issued: 2023-06-22

บทความ/Article

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BibliograpyCitation : In Mae Fah Luang University. School of Science. The Pure and Applied Chemistry International Conference 2023 (PACCON 2023) (pp.619-624). Chiang Rai : Mae Fah Luang University

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