Behavior modified properties of DEET and components of vetiver oil against Aedes aegypti and Anopheles minimus

Name: Rungarun Tisgratog

LCSH: Kasetsart University -- Dissertations. Ph.D. (Entomology) 2016

Classification :.LCCS: QL536

LCSH: Kasetsart University. Department of Entomology -- Dissertations

LCSH: Essences and essential oils -- Utilization

LCSH: Vetiver -- Utilization

LCSH: Malaria

LCSH: Mosquitoes as carriers of disease

LCSH: Mosquitoes

LCSH: Anopheles

Abstract: From our investigation, we identified 37 plant species within 14 plant families that showed some mosquito repellent properties. Of these, 9 plant species were characterized using an excito-repellency test system against several Thai mosquito species. Results from these studies revealed that five essential oils extracted from plants demonstrated promising insect repellent activity. These active ingredients show promise for further development into formulations that may serve as alternatives to DEET or possibly be used as natural biopesticides to kill mosquitoes. A novel non-contact repellency assay system (NCRAS) was designed and evaluated as a possible alternative method for testing compounds that repel or inhibit mosquito bites. DEET and Aedes aegypti were used in a controlled laboratory setting. Using two study designs, a highly significant difference were seen between DEET-treated and untreated skin placed behind the protective screens indicating that DEET was detected and acting as deterrence to mosquito landing and probing behavior. However, a second study showed significant differences between screened and unscreened, indicating the screen mesh might restrict the detection of DEET and thus influences landing/biting response. These findings indicate the prototype NCRAS shows good promise but requires further evaluation and possible modification in design. In additional, contact irritant, spatial repellent and toxic actions of Anopheles minimus exposed to 6 components of vetiver oil (valencene, terpinen-4-ol, isolongifolene, vetiverol, α-terpineol and vetivone) were performed by using the high throughput screening assay system (HITSS) at 4 concentrations. The strong contact irritancy action was investigated from isolongifolene at 5 % (81.7) and the highest mean percent escaping was investigated from SRA is alpha-terpineol at 5 % (41.0). The evaluation of the dose response relationship with these compounds is vital to understanding how best to used the bioactive compounds against biting insects.

Kasetsart University. Office of the University Library

Address: Bangkok

Email: tdckulib@ku.ac.th

Name: Theeraphap Chareonviriyaphap

Role: Thesis Advisor

Name: John Paul Grieco

Role: Thesis Co-Advisor

Name: Unchalee Sanguanpong

Role: Thesis Co-Advisor

Created: 2016

Modified: 2023-06-12

Issued: 2023-06-12

วิทยานิพนธ์/Thesis

application/pdf

URL: https://kasetsart.idm.oclc.org/login?url=http://lib.ku.ac.th/kuthesis/2559/rungarun-tis-all.pdf

CallNumber: QL536.R86

eng

DegreeName: Doctor of Philosophy

Level: Doctoral Degree

Descipline: Entomology

Grantor: Kasetsart University

©copyrights Kasetsart University

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