Effects of emulsifier and liquid lipid on the physiochemical properties of Piper retrofractum fruit extract loaded nanostructure lipid carriers

Name: Kavee Srichaivatana

Organization : Naresuan University. Faculty of Pharmaceutical Sciences

Name: Anan Ounaroon

Organization : Naresuan University. Faculty of Pharmaceutical Sciences

Name: Waree Tiyaboonchai

Organization : Naresuan University. Faculty of Pharmaceutical Sciences

Email : wareet@nu.ac.th

keyword: Piper retrofractum

LCSH: Emulsions (Pharmacy)

LCSH: Plant extracts -- Therapeutic use

LCSH: Drug delivery systems

Abstract: Antioxidant activities of aqueous Oolong tea extracts from different extraction conditions including stirring at 80 °C for 5 and 10 min and soaking in hot water (80 °C) for 5 and 10 min were investigated. The extract from 5 min stirring at 80 °C showed the highest total phenolic content (2351.04 mg gallic acid equivalent) and antioxidant activities (with 28.59 mM ascorbic acid equivalent for DPPH radical scavenging, 19.28 mM FeSO4 for ferrous reducing power, and 27.39 mM trolox equivalent for ABTS). In addition, the extract could absorb UV in range of 250–380 with maximum absorption at 280 nm. Its UV protection with 5 (ultra) values of boots star rating was determined by SPF analyzer. HPLC analysis of this extract revealed the presence of caffeine, epicathechin gallate, epicatechin and cathechin. To enhance stability and penetration of the extract, chitosan (CS)– tripolyphosphate (TPP) nanoparticles were developed by the ionic gelation method. Tea extract-loaded CS-TPP nanoparticles were successfully prepared by mixing chitosan, TPP and extract in the ratio of 6:1:3. The size of nanoparticles was observed in range of 200–400 d.nm.

King Mongkut's University of Technology North Bangkok. Central Library

Address: BANGKOK

Email: library@kmutnb.ac.th

Created: 2016

Modified: 2023-01-04

Issued: 2023-01-04

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BibliograpyCitation : In Chemical Society of Thailand under the Patronage of Professor Dr. HRH Princess Chulabhorn and Chulalongkorn University Faculty of science. Pure and Applied Chemistry International Conference (PACCON 2016) (pp.1138-1141). Bangkok : Chemical Society of Thailand under the Patronage of Professor Dr. HRH Princess Chulabhorn

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